II. Causes: Endocrine Causes

III. Causes: Nutrition

  1. Vitamin D Deficiency (very common in elderly)
    1. Community-dwelling elderly: 36% men, 47% women
    2. Long-term Care Residents: 80-100% Prevalence
  2. Alcoholism or Alcohol use more than 2 drinks per day
  3. Gastric Bypass Surgery
  4. Malabsorption syndromes (esp. Celiac Sprue)
  5. Malnutrition
  6. Vitamin A Excess
  7. Anorexia Nervosa (and Female Athlete Triad)
  8. Bulimia Nervosa
  9. Calcium deficiency (e.g. Hypercalciuria)

V. Causes: Malignancy

  1. Multiple Myeloma
  2. Leukemia
  3. Lymphoma
  4. Ectopic ACTH Syndrome

VI. Causes: Genetic Syndromes

  1. Osteogenesis imperfecta
  2. Marfan Syndrome
  3. Ehlers-Danlos Syndrome
  4. Homocystinuria
  5. Glycogen Storage Diseases
  6. Hypophosphatasia

VII. Causes: Neurologic

  1. Seizure Disorder
  2. Multiple Sclerosis
  3. Parkinonism
  4. Spinal cord injury
  5. Cerebrovascular Accident

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Ontology: Secondary generalized osteoporosis (C0473771)

Concepts Acquired Abnormality (T020)
SnomedCT 240157009
English Second general osteoporosis, Secondary generalised osteoporosis, Secondary generalized osteoporosis, Secondary generalized osteoporosis (disorder)
Spanish osteoporosis generalizada secundaria (trastorno), osteoporosis generalizada secundaria