II. Definition

  1. Hypokalemia with Urine Potassium < 20 meq/day

III. Causes: Normal Acid-Base Status and Hypokalemia

  1. Chronic Diarrhea
  2. Acute Leukemia
  3. Aminoglycosides
  4. High dose Penicillin
  5. Hypomagnesemia
    1. Intracellular Magnesium is not reflected by Serum Magnesium level
    2. Consider empiric Magnesium Replacement in refractory Hypomagnesemia
  6. Constant GI loss and inadequate intake (<10-20 meq/day)
  7. Skin losses from sweating

IV. Causes: Metabolic Acidosis and Hypokalemia

  1. Diarrhea
  2. Amphotericin
  3. Diabetic Ketoacidosis
  4. Laxative abuse
  5. Intestinal or biliary fistula
  6. Ureterostomy
  7. Toluene

V. Causes: Metabolic Alkalosis and Hypokalemia

  1. Gastrointestinal loss (Consider Bulimia)
    1. Vomiting
    2. Nasogastric suction
  2. Discontinued Diuretics

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