II. Background

  1. Derivations
    1. LSD semisynthetically derived from ergot alkaloids
    2. Mescaline naturally derived from peyote
    3. Psilocybin naturally derived from Psilocybe
  2. Pharmacokinetics
    1. LSD (50-400 ug): 8-12 hour duration
    2. Mescaline (250-600 mg): 8-12 hour duration
    3. Psilocybin (10-50 mg): 6-8 hour duration

III. Forms or Street Names

  1. Lysergic Acid Diethylamide (LSD)
    1. Acid
    2. Sugar
    3. Cubes
    4. Trips
    5. Windowpane
    6. Blotter
  2. Mescaline
    1. Buttons
    2. Beans
    3. Cactus
  3. Psilocybin
    1. Magic Mushrooms
    2. Mushroom
    3. Los ninos

IV. Signs

  1. Hyper-suggestible state

V. Signs: Toxicity (Amphetamine-like reaction)

VI. Management: Toxicity

  1. Provide calm and supportive environment

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Ontology: Hallucinogen Use Disorders (C0018532)

Concepts Mental or Behavioral Dysfunction (T048)
English Hallucinogen Use Disorders

Ontology: Lysergic Acid Diethylamide (C0024334)

Definition (MSH) Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
Definition (CSP) semisynthetic derivative of ergot; it has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover; it is a potent hallucinogen and psychotomimetic.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109) , Hazardous or Poisonous Substance (T131)
MSH D008238
SnomedCT 15698006
LNC LP16179-1, MTHU006728
English Diethylamide, Lysergic Acid, LSD, LSD 25, LSD-25, Lysergic Acid Diethylamide, Lysergide, Acid Diethylamide, Lysergic, lysergic acid diethylamide, Ergoline-8-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-, (8beta)-, LSD - D-Lysergic acid, D-Lysergic acid, D-Lysergic Acid Diethylamide, Lysergic Acid Diethylamide [Chemical/Ingredient], lysergic acid diethylamide (LSD), lsd-25, lysergide, Lysergate diethylamide, LYSERGIDE, Lysergic acid diethylamide, Lysergic acid diethylamide (substance), LSD (Drug)
Swedish LSD
Czech diethylamid kyseliny lysergové, LSD
Finnish Lysergihapon dietyyliamidi
Russian LIZERGID, LIZERGINOVOI KISLOTY DIETILAMID, LSD, ЛИЗЕРГИД, ЛИЗЕРГИНОВОЙ КИСЛОТЫ ДИЭТИЛАМИД, ЛСД
French LSD, Lysergide
Italian LSD, Lisergide, LSD-25, Dietilammide dell'acido lisergico
Polish Dietyloamid kwasu lizergowego, Dwuetyloamid kwasu lizergowego
Japanese リセルギド, リセルグ酸ジエチルアミド, リゼルギン酸ジエチルアミド
Spanish dietilamida de ácido lisérgico (sustancia), dietilamida de ácido lisérgico, lisergida, LSD, Lisergida, Dietilamida del Ácido Lisérgico
German LSD, Lysergid, Lysergsäurediethylamid
Portuguese LSD, Dietilamida do Ácido Lisérgico, Lisergida

Ontology: Mescaline (C0025460)

Definition (MSH) Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church.
Concepts Hazardous or Poisonous Substance (T131) , Organic Chemical (T109)
MSH D008635
SnomedCT 229008008, 373780001, 83192000
LNC LP17987-6, MTHU003041
English Mescaline, Trimethoxyphenethylamine, Benzeneethanamine, 3,4,5-trimethoxy-, 3,4,5-Trimethoxyphenethylamine, Mescalin substance of abuse, Peyote extract, Mescalin, mescaline in any form, Mescaline [Chemical/Ingredient], mescalin, mescaline, Mescalin substance of abuse (substance), Mescaline (product), Mescaline (substance)
Swedish Meskalin
Czech meskalin
Finnish Meskaliini
Russian MEZKALIN, MESKALIN, PEIOT, TRIMETOKSIFENETILAMIN, МЕЗКАЛИН, МЕСКАЛИН, ПЕЙОТ, ТРИМЕТОКСИФЕНЕТИЛАМИН
Japanese メズカリン, メスカリン, メッカリン, ペヨーテ, トリメトキシフェネチルアミン
Croatian MESKALIN
Polish Meskalina
Spanish mescalina, sustancia de abuso (sustancia), extracto de peyote, mescalina, sustancia de abuso, Peyotl, mescalina (producto), mescalina (sustancia), mescalina, Mescalina, Trimetoxifenetil Amina
Portuguese Peyote, Peyotl, Mescalina, Trimetoxifenetilamina
French Mescaline
German Mescalin, Trimethoxyphenethylamin
Italian Mescalina