II. Epidemiology

  1. Anxiety Disorder Incidence (U.S.): 16%
  2. Family physicians treat 90% of anxiety patients
    1. Refer <10% of patients to psychiatry
  3. Elderly have lower Incidence of anxiety
    1. Elderly women more affected than men
    2. Often associated with depression

III. Pathophysiology

  1. Hyperarousal state
  2. Begins in Brainstem reticular formation
    1. Locus Ceruleus (Secretes Norepinephrine)
    2. Dorsal and medial raphe nuclei (Secretes Serotonin)

IV. Differential Diagnosis

VI. Symptoms

  1. See Anxiety Symptoms
  2. Excessive Worry
  3. May affect relationships

VII. Lab: Evaluation for Anxiety Secondary Causes

  1. Standard Studies
    1. Serum Chemistry profile
      1. Serum Glucose
      2. Serum Calcium
      3. Serum phosphate
    2. Thyroid Stimulating Hormone (TSH)
    3. Urine Drug Screen
  2. Studies if specifically indicated
    1. Serum Cortisol
    2. Urine Catecholamines

VIII. Diagnostics: Evaluation for Anxiety Secondary Causes

  1. Standard Studies
    1. Electrocardiogram
  2. Studies if specifically indicated
    1. Electroencephalogram (EEG)
    2. Vestibular testing
    3. Echocardiography

IX. Evaluation

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Ontology: Anxiety Disorders (C0003469)

Definition (NCI) A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety.
Definition (NCI_CTCAE) A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus.
Definition (CSP) general term for the group of specific, anxiety-related, avoidance- prone disorders listed as NTs.
Definition (PSY) Disorders characterized by anxiety or dread without apparent object or cause. Symptoms include irritability, anxious expectations, pangs of conscience, anxiety attacks, or phobias.
Definition (MSH) Persistent and disabling ANXIETY.
Concepts Mental or Behavioral Dysfunction (T048)
MSH D001008
ICD10 F41.9
SnomedCT 191703000, 192405006, 65673007, 197480006
DSM4 300.00
LNC MTHU020812
English Disorder, Anxiety, Disorders, Anxiety, Anxiety Disorder NOS, Anxiety disord unspecified, Anxiety disorder, unspecified, [X]Anxiety disord unspecified, [X]Anxiety disorder, unspecified, Anxiety disorders, ANXIETY DIS, anxiety disorder (diagnosis), anxiety disorder, Anxiety Disorders, Anxiety NOS, Anxiety Disorders [Disease/Finding], anxiety disorder nos, anxiety disorders, [X]Anxiety disorder, unspecified (disorder), Anxiety, Anxiety disorder, Anxiety disorder (disorder), Anxiety disorder, NOS, Anxiety disorder [Ambiguous], Anxiety Disorder, Disorder;anxiety
Italian Disturbo ansioso, Disturbi d'ansia
Swedish Ångeststörningar
Japanese フアンショウガイ, 不安神経症, 神経症性不安状態, 不安状態-神経症性, 不安ノイローゼ, 神経症-不安, 不安障害
Czech úzkostné poruchy, anxiózní poruchy, Úzkostná porucha
Finnish Ahdistuneisuushäiriöt
Russian NEVROZY STRAKHA, STRAKHA NEVROZY, TREVOGI SOSTOIANIIA NEVROTICHESKIE, BOIAZNI SOSTOIANIIA, БОЯЗНИ СОСТОЯНИЯ, НЕВРОЗЫ СТРАХА, СТРАХА НЕВРОЗЫ, ТРЕВОГИ СОСТОЯНИЯ НЕВРОТИЧЕСКИЕ
Spanish Trastorno de ansiedad, [X]trastorno de ansiedad, no especificado, [X]trastorno de ansiedad, no especificado (trastorno), trastorno de ansiedad (concepto no activo), Trastornos de Angustia, trastorno de ansiedad (trastorno), trastorno de ansiedad, Trastornos de Ansiedad
German Angststoerung, nicht naeher bezeichnet, Angststoerung, Angststörungen
Korean 상세불명의 불안 장애
Portuguese Transtornos de Ansiedade, Distúrbios de Ansiedade, Transtornos de Angústia, Transtornos Ansiosos, Pertubação de ansiedade
Polish Zaburzenia lękowe
Hungarian Szorongásos zavar
Norwegian Angstforstyrrelser, Angstlidelser
Croatian ANKSIOZNI POREMEĆAJI
Dutch Angststoornis, niet gespecificeerd, angststoornis, Angststoornis, Angststoornissen
French Trouble anxieux, Troubles anxieux, Troubles de l'anxiété