II. Indications

III. Pharmacokinetics: Nerve Agent Exposure

  1. Significantly enhances post-exposure antidote for Soman
  2. Does not enhance antidote for other Nerve Agents
  3. Raises Soman LD50 by several fold

IV. Dosing: Nerve Agent Exposure

  1. Pyridostigmine 30 mg PO every 8 hours before exposure

V. Precautions: Nerve Agent Exposure

  1. Pyridostigmine does not protect against exposure
  2. Nerve Agent Exposures must be treated with Antidote

VI. References

  1. (1998) USAMRICD Chemical Casualties Handbook, p. 58-9

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Cost: Medications

pyridostigmine (on 8/17/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
PYRIDOSTIGMINE BR 60 MG TABLET Generic $0.58 each
PYRIDOSTIGMINE ER 180 MG TAB Generic $13.44 each

Ontology: Pyridostigmine (C0034261)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D011729
SnomedCT 373344003, 59953007
LNC LP17869-6, MTHU024724
English PYRIDOSTIGMINE, pyridostigmine, Pyridostigmine (product), Pyridostigmine (substance), Pyridostigmine
Spanish piridostigmina (producto), piridostigmina (sustancia), piridostigmina