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Ferric Subsulfate

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Ferric Subsulfate, Ferric Subsulfate Solution, Monsel's Slution, AtrinGen

  • Indications
  1. Control of bleeding from small wounds on skin or mucosa (e.g. Colposcopy biopsy)
  • Background
  1. One of the oldest Hemostatic Agents (described by Monsel in the 1850s)
  • Mechanism
  1. Topical Hemostatic Agent
  2. Denatures and coagulates proteins to form a membrane over small blood vessels
  • Technique
  1. Clean bleeding site and apply local pressure
  2. Insert cotton swab into Monsel's solution and stir to mix
  3. Apply cotton swab to bleeding site
  • Adverse Effects
  1. May cause discoloration of tissue to which it has been applied
  • References
  1. Berry in Schrage (2013) Topical Hemostatic Agents, Medscape Emedicine
  2. Peralta in Sanfrey (2013) Overview of Topical Hemostatic Agents and tissues adhesives used in the operating room, UpToDate, Wolters-Kluwer
  3. Achneck (2010) Ann Surg 251(2):217-28 [PubMed]