II. Causes

  1. Similar list of causes as Bronchiolitis Obliterans
  2. Idiopathic form: Cryptogenic Organizing Pneumonia

III. Presentation

  1. Slowly resolving Pneumonia over weeks to months
    1. Consider in unresolved community acquired Pneumonia
  2. May be associated with fever and Sore Throat

IV. Symptoms

  1. Non-productive cough
  2. Dyspnea

V. Signs

  1. Diffuse rales
  2. Rare Wheezes

VI. Imaging: Chest XRay

  1. Variable appearance (may be normal)
  2. Bilateral ground glass, patchy appearance (most common)
  3. Diffuse nodular pattern

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Ontology: Bronchiolitis Obliterans Organizing Pneumonia (C0242770)

Definition (MSH) An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.
Definition (NCI) A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Obstructive symptoms are limited to smokers. There are patchy polypoid masses of intra-alveolar granulation tissue in small airway lumina and alveolar ducts. "Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli.(MeSH)
Concepts Disease or Syndrome (T047)
MSH D018549
ICD9 516.36
ICD10 J84.116
SnomedCT 129458007
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Finnish BOOP
Italian BOOP, Polmonite criptogenica organizzata, Bronchiolite obliterante causante la polmonite, Bronchiolite obliterante con polmonite in fase di organizzazione, Polmonite in fase di organizzazione criptogenetica, Bronchiolite obliterante con polmonite in via di organizzazione
Russian BRONKHIOLIT OBLITERIRUIUSHCHII S PNEVMONIEI, KRIPTOGENNAIA ORGANIZUIUSHCHAIA PNEVMONIIA, КРИПТОГЕННАЯ ОРГАНИЗУЮЩАЯ ПНЕВМОНИЯ, БРОНХИОЛИТ ОБЛИТЕРИРУЮЩИЙ С ПНЕВМОНИЕЙ
Japanese 特発性器質化肺炎, キシツカハイエンヲトモナウヘイソクセイサイキカンシエン, 器質化肺炎を伴う閉塞性細気管支炎, BOOP, トクハツセイキシツカハイエン, BOOP, 器質化肺炎を伴った閉塞性細気管支炎, 閉塞性細気管支炎・器質化肺炎, 肺炎-特発性器質化, 器質化肺炎-特発性
Spanish Neumonía en Organización Criptogénica, Bronquiolitis Obliterante con Neumonía en Organización, Neumonía organizada criptogénica, Bronquiolitis obliterante con neumonía organizada, Bronquiolitis obliterante con neumonía organizativa, Neumonía organizativa criptogénica, Neumonía Criptogénica en Organización, BOOP, Neumonía con Organización Criptogénica, bronquiolitis obliterante con neumonía en desarrollo, bronquiolitis obliterante y neumonía con organización (trastorno), bronquiolitis obliterante y neumonía con organización, neumonía criptógena en desarrollo (trastorno), neumonía criptógena en desarrollo, BONO
French POC (Pneumonie Organisée Cryptogénique), Bronchiolite oblitérante organisée en pneumonie, Pneumonie organisée cryptogénique, Bronchiolite oblitérante avec organisation pneumonique, Bronchiolite oblitérante avec pneumonie organisée, Bronchiolite oblitérante avec pneumonie organisée (BOOP), Pneumonie idiopathique organisée, BOOP, Pneumopathie organisée cryptogénique
Dutch cryptogene organiserende longontsteking, bronchiolitis obliterans met beginnende longontsteking, bronchiolitis obliterans met organiserende pneumonie, BOOP, Bronchiolitis obliterans met organiserende pneumonie
German Kryptogen organsierende Pneumonie, Bronchiolitis obliterans mit organisierter Pneumonie, kryptogen organisierte Pneumonie, BOOP, Bronchiolitis obliterans mit organisierender Pneumonie
Portuguese Bronquiolite obliterante com pneumonia organizada, Pneumonia de organização criptogénica, Pneumonia em Organização Criptogênica, Pneumonia por Bronquiolite Obliterante em Organização, Bronquiolite obliterante com pneumonia em organização, Pneumonia em organização criptogénica, Pneumonia Criptogênica em Organização, BOOP
Czech Obliterující bronchiolitická pneumonie, Kryptogenní organizující se pneumonie, Kryptogenicky organizovaný zánět plic, Bronchiolitis obliterans s organizujícím zánětem plic, Obliterující bronchiolitida s organizující se pneumonií, kryptogenní organizující se pneumonie, bronchiolitida obliterující s organizující se pneumonií, BOOP, obliterující bronchiolitida s organizující se pneumonií
Swedish Kryptogen organiserad pneumoni
Polish Zapalenie płuc kryptogenne organizujące się, Organizujące się kryptogenne zapalenie płuc, Zarostowe zapalenie oskrzelików z organizującym się zapaleniem płuc, Zapalenie płuc z zarostowym zapaleniem oskrzelików, Kryptogenne organizujące się zapalenie płuc, BOOP, Zapalenie płuc organizujące się kryptogenne
Hungarian Cryptogen organizálódó pneumonia, BOOP, Bronchiolitis obliterans szervülő pneumoniával
Norwegian BOOP, Kryptogen organiserende pneumoni, Organiserende pneumoni, Bronchiolitis obliterans organiserende pneumoni