Urology Book

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Prostate Radiotherapy

Aka: Prostate Radiotherapy, External Beam Prostate Radiotherapy
  1. See Also
    1. Prostate Seed Implant Radiotherapy
  2. Indications
    1. Localized Prostate Cancer (Stages A to C)
  3. Technique
    1. External beam radiation applied daily for 4 to 6 weeks
  4. Efficacy:
    1. First 10 years: As effective as Radical Prostatectomy
    2. After 10 years: Tumor recurrence may be more rapid
  5. Advantages over Radical Prostatectomy
    1. Well tolerated outpatient therapy
    2. No surgical risks of bleeding or anesthesia
  6. Disadvantages compared with Radical Prostatectomy
    1. No hisotologic data from Prostate tumor
    2. No lymph node data for Prostate Cancer Staging
  7. Adverse Effects
    1. Acute irritative uropathy for first 3 months
      1. Urinary urgency
      2. Dysuria and Pelvic Pain
      3. Urinary frequency
    2. Urinary Incontinence (1%)
    3. Impotence (30 to 50%)
    4. Rectal irritation (3 to 10%)
      1. Diarrhea
      2. Stool Urgency
      3. Tenesmus
      4. Rectal Bleeding
  8. References
    1. Middleton (1996) CA Cancer J Clin 46(4):249-53 [PubMed]
    2. Naitoh (1998) Am Fam Physician 57(7):1531-9 [PubMed]
    3. Williams (1996) Postgrad Med 100(3): 105-20 [PubMed]

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