Urology Book

http://www.fpnotebook.com/

Pentosan polysulfate

Aka: Pentosan polysulfate, Elmiron
  1. Indications
    1. Interstitial Cystitis
  2. Mechanism
    1. Semisynthetic glucosaminoglycan
  3. Dosing
    1. Pentosan polysulfate 100 mg PO tid
  4. Efficacy
    1. Symptoms improve as much as 50% in controlled trials
    2. Response may not be seen for 3 to 6 months
  5. Adverse Effects
    1. Diarrhea
    2. Dyspepsia
    3. Alopecia (reversible)
    4. Headache
    5. Rash
    6. Dizziness
    7. Abdominal Pain
    8. Liver function abnormalities (<4%)
  6. References
    1. Bade (1997) Br J Urol 79:168-71
    2. Parsons (1993) J Urol 150:845-8
Medication Costs
elmiron (on 4/19/2017 at Medicaid.Gov Pharmacy Drug pricing)
ELMIRON 100 MG CAPSULE $7.98 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Elmiron (C0600293)

Concepts Pharmacologic Substance (T121) , Carbohydrate (T118)
MSH D010426
English pentosan polysulfate sodium (Elmiron), elmiron, Elmiron
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Pentosan Polysulfate (C0600296)

Definition (NCI_NCI-GLOSS) A drug used to relieve pain or discomfort associated with chronic inflammation of the bladder. It is also being evaluated for its protective effects on the gastrointestinal tract in people undergoing radiation therapy.
Definition (NCI) A semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is unknown, pentosan polysulfate may act as a buffer to control cell permeability by preventing irritating solutes from reaching cells coated with it. Administered orally, excreted pentosan polysulfate adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis (IC), a complication of some chemotherapies. This agent also exhibits anticoagulant and fibrinolytic properties. (NCI04)
Concepts Pharmacologic Substance (T121) , Carbohydrate (T118)
MSH D010426
SnomedCT 109116008, 372571007
English Polysulfate, Pentosan, pentosan polysulphate, pentosanpolysulfate, pentosan polysulfate, PENTOSAN POLYSULFATE, Pentosan polysulfate (product), Pentosan polysulfate (substance), Pentosan polysulfate, Pentosan polysulphate, Xylan Hydrogen Sulfate, Xylan Polysulfate, Pentosan Polysulfate
Portuguese Pentosana Polissulfato
Spanish Pentosan Polisulfato, polisulfato de pentosan (sustancia), pentosano polisulfato, pentosano polisulfato (sustancia), polisulfato de pentosan, polisulfato de pentosano, polisulfato de pentosano (producto), pentosano polisulfato (producto), polisulfato de pentosano (sustancia)
German Pentosanpolysulfat
Sources
Derived from the NIH UMLS (Unified Medical Language System)


You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree