Urology Book

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Prostate Cancer Staging

Aka: Prostate Cancer Staging, Prostate Cancer Stage, TNM Prostate Cancer Staging, ABCD Prostate Cancer Staging, Whitmore Staging
  1. See Also
    1. Prostate Cancer
  2. Background
    1. TNM staging replaces ABCD\Whitmore Prostate Staging
  3. Classification: Primary Tumor (T)
    1. Stage T1: Not palpable
      1. Stage T1a: Incidentally cancer present in less than 5% of tissue sampled (e.g. on TURP)
      2. Stage T1b: Incidentally cancer present in greater than 5% of tissue sampled (e.g on TURP)
      3. Stage T1c: Elevated PSA leasd to needle biopsy which revealed positive cancer in tissue sample
    2. Stage T2: Palpable, but limited to Prostate
      1. Stage T2a: Cancer involvement <50% of only one of the two Prostate lobes
      2. Stage T2b: Cancer involvement >50% of only one of the two Prostate lobes
      3. Stage T2c: Cancer involvement in both of the two Prostate lobes
    3. Stage T3: Local spread beyond the Prostate capsule
      1. Stage T3a: Tumor spread through the capsule
      2. Stage T3b: Tumor invasion of either Seminal Vessicle
    4. Stage T4
      1. Regional spread
  4. Classification: Regional Lymph Nodes (N)
    1. Stage N0: No spread to regional lymph nodes
    2. Stage N1: Spread to regional luymph nodes
  5. Classification: Distant Metastases (M)
    1. Stage M0: No distant metastasis
    2. Stage M1: Distant metastasis
      1. Stage M1a: Spread to lymph nodes outside the regional nodes
      2. Stage M1b: Spread to bone
      3. Stage M1c: Spread to non-bony tissue (with or without bone involvement)
  6. Classification: Whitmore Staging (replaced by above TNM Staging)
    1. Stage A
      1. Stage A1: Single impalpable lesion (<5% of gland)
      2. Stage A2: Impalpable microscopic lesion (>5% of gland)
    2. Stage B
      1. Stage B1: Palpable Nodule in single lobe
      2. Stage B2: Palpable Nodules
    3. Stage C
      1. Stage C1: Localized disease extending beyond gland
      2. Stage C2: Localized disease includes Seminal Vessicles
    4. Stage D
      1. Stage D1: Pelvic lymph node involvement
      2. Stage D2: Bone metastases or distant spread

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