Urology Book

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Angiokeratoma

Aka: Angiokeratoma, Angiokeratoma of Fordyce, Angiokeratoma of the Glans Penis
  1. See Also
    1. Penile Lesion
  2. Epidemiology
    1. Prevalence: <1%
    2. More common in white patients
    3. Age of onset >40 years
  3. Symptoms
    1. Typically asymptomatic
    2. May rarely bleed or be pruritic
  4. Signs
    1. Red-blue Papules
    2. Typically 1-2 mm in size
    3. Distribution
      1. Clustered on the glans penis, often linear along the margin
      2. May occur on Scrotum, groin, thighs, and abdominal wall
      3. Lesions on the penile shaft, suprapubic region or Sacrum suggest Fabry disease and require referral (see below)
  5. Differential Diagnosis
    1. Pearly Penile Papules
    2. Fabry Disease (Lysosomal Storage Disease)
      1. May present with Angiokeratomas on the penile shaft, suprapubic region or Sacrum
      2. Requires urgent Consultation
  6. Management: Symptomatic Cases
    1. Electrocautery
    2. Cryotherapy
    3. Laser ablation
    4. Surgical excision
  7. References
    1. Leis-Dosil (2007) Dermatol Online J 13(2): 19 [PubMed]
    2. Teichman (2010) Am Fam Physician 81(2): 167-74 [PubMed]

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