Mental Health Book

Hallucinogen Use Disorders

Inhalants

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Phencyclidine

Aka: Phencyclidine, PCP
  1. See Also
    1. Chemical Dependency
    2. Substance Abuse Evaluation
  2. Class
    1. Hallucinogen
    2. Schedule II
  3. Street Names
    1. Angel dust
    2. Hog
    3. Horse Tranquilizer
  4. Pharmacokinetics
    1. PCP (2-10 mg): 3-18 hour duration
  5. Toxicity
    1. General Toxicity
      1. Psychosis
      2. Violent Behavior
    2. Severe Overdose
      1. Coma
      2. Seizure
      3. Hypotension or Hypertension
      4. Muscular rigidity to severe Hypothermia
      5. Rhabdomyolysis
  6. Toxicity Management
    1. Consider Restraints for Violent Behavior
      1. Physical Restraints
      2. Chemical Restraints
    2. Benzodiazepines
    3. External cooling
    4. Dantrolene (Muscle Relaxant) Indications
      1. Severe hyperthermia
      2. Rhabdomyolysis

Phencyclidine (C0031381)

Definition (NCI) Developed as an anesthetic for humans in 1959. Its use was discontinued due to extreme side effects that included delirium, confusion, visual disturbances, hallucinations and violence; some evidence of long-term memory disorders and schizophrenia-like syndrome has been observed. Phencyclidine, a substance of abuse also know as 'angel dust', can cause physical and psychological distresses, such as coma, seizures, convulsions, respiratory depression, and cardiac problems.
Definition (MSH) A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.
Definition (PSY) Piperadine having hallucinogenic, anesthetic, and analgesic properties.
Definition (CSP) this drug is both a legitimate prescription anesthetic and a notoriously abused street drug also known as "angel dust."
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D010622
SnomedCT 228996005, 9721008
LNC LP14566-1, MTHU001586
English 1-(1-Phenylcyclohexyl)piperidine, Phencyclidine, Angel Dust, Dust, Angel, phencyclidine, Piperidine, 1-(1-phenylcyclohexyl)-, Phencyclidine substan of abuse, Phencyclidine substance of abuse, PCP - Phencyclidine, PHENCYCLIDINE, Phencyclidine [Chemical/Ingredient], angel dust, phencyclidines, phencyclidine(PCP), phencyclidine (Schedule I substance), Phencyclidine substance of abuse (substance), PCP, Angel dust, Phencyclidine (substance)
Swedish Fencyklidin
Czech fencyklidin
Finnish Fensyklidiini
Russian SERNIL, FENTSIKLIDIN, FENTSIKLIDINGIDROKHLORID, СЕРНИЛ, ФЕНЦИКЛИДИН, ФЕНЦИКЛИДИНГИДРОХЛОРИД
Italian 1-(1-Fenil cicloesano)piperidina, Polvere d'angelo, Fenciclidina
Polish Fencyklidyna
Japanese フェンサイクリジン, フェンシクリジン
Spanish abuso de enciclidina, abuso de enciclidina (sustancia), fenciclidina (sustancia), fenciclidina, polvo de ángel, Fenciclidina
French Phencyclidine
German Phencyclidin
Portuguese Fenciclidina
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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