Pharmacology Book

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Patch Delivered Medication

Aka: Patch Delivered Medication, Transdermal Drug, Medication Patch
  1. Precautions
    1. Patch is heat sensitive
      1. Increases absorption and decreases duration
      2. Affected by fever, Sun Exposure, heating pads, saunas
      3. Could dangerously increase levels (e.g. Fentanyl)
    2. Avoid cutting patches unless specifically allowed
      1. Patches with evenly distributed medication may be cut (e.g. Lidoderm)
      2. Avoid cutting patches with drug reservoir (e.g. Androderm, Nicoderm CQ)
      3. Avoid cutting patches for which exact dosing must be maintained (e.g. Fentanyl)
    3. Remove patches before entering MRI
      1. Many patches have a metallic backing
    4. Patch disposal
      1. FDA recommends Flushing some patches with diversion potential (e.g. Fentanyl)
      2. Take-Back programs may accept patches for disposal
      3. Other patches may be folded in half (adherent sides together) and discarded
  2. References
    1. (2017) Presc Lett 24(7)

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