Neurology Book

http://www.fpnotebook.com/

Ropinirole

Aka: Ropinirole, Requip
  1. See Also
    1. Dopamine Agonist
    2. Mirapex (Pramipexole)
  2. Indications
    1. Parkinson's Disease
    2. Restless Leg Syndrome
  3. Dosing: Restless Leg Syndrome
    1. Start: Requip 0.25 mg orally taken 2-3 hours before bedtime
    2. Interval for increasing dose: 3-7 days
    3. Titrating dose: Increase at set interval as above by one tablet if ineffective at current dose
      1. Start at 0.25 mg one tablet nightly for set interval in days
      2. Increase to two tablets (0.50 mg) nightly for set interval if ineffective at 0.25 mg
      3. Increase to three tablets (0.75 mg) nightly for set interval if ineffective at 0.50 mg
    4. Maximum dose: 6 tablets (1.5 mg) taken at bedtime
    5. Stopping: No titration needed
  4. Adverse Effects (similar to Mirapex)
    1. Nausea (common)
    2. Drowsiness (Limited to higher dosages)
      1. May be sudden, severe without warning
      2. May occur up to one year after starting Mirapex
      3. Has resulted in falling asleep while driving
    3. Augmentation of Restless Leg Symptoms
      1. Occurs in 25% of RLS patients on longterm therapy
      2. May progress in severity, and involve arms, trunk
      3. Often better if dose timing changed to earlier in day
      4. May be worse if dose increased
    4. Other uncommon adverse effects (rare at low dose)
      1. Hallucinations
      2. Pathologic Gambling (related to Dopamine receptor agonist activity, D3)
      3. Orthostatic Hypotension
      4. Hypersexuality
Medication Costs
ropinirole (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
ROPINIROLE HCL 0.25 MG TABLET Generic $0.09 each
ROPINIROLE HCL 0.5 MG TABLET Generic $0.07 each
ROPINIROLE HCL 1 MG TABLET Generic $0.07 each
ROPINIROLE HCL 2 MG TABLET Generic $0.09 each
ROPINIROLE HCL 3 MG TABLET Generic $0.11 each
ROPINIROLE HCL 4 MG TABLET Generic $0.11 each
ROPINIROLE HCL 5 MG TABLET Generic $0.13 each
ROPINIROLE HCL ER 12 MG TABLET Generic $6.06 each
ROPINIROLE HCL ER 2 MG TABLET Generic $1.15 each
ROPINIROLE HCL ER 4 MG TABLET Generic $2.82 each
ROPINIROLE HCL ER 6 MG TABLET Generic $3.72 each
ROPINIROLE HCL ER 8 MG TABLET Generic $3.71 each
requip (on 1/1/2017 at Medicaid.Gov Pharmacy Drug pricing)
REQUIP XL 2 MG TABLET Generic $1.15 each
REQUIP XL 4 MG TABLET Generic $2.82 each
REQUIP XL 6 MG TABLET Generic $3.72 each
REQUIP XL 8 MG TABLET Generic $3.71 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

ropinirole (C0244821)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C046649
SnomedCT 108473005, 372499000
English 4-(2-(di-n-propylamino)ethyl)-2(3H)-indolone, ropinirol, ropinirole, ropinirole [Chemical/Ingredient], rOPINIRole, ROPINIROLE, Ropinirole, Ropinirole (product), Ropinirole (substance)
Spanish ropinirola (sustancia), ropinirol (sustancia), ropinirola, ropinirol (producto), ropinirol
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Requip (C0593342)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C046649
English Requip, requip, GlaxoSmithKline brand of ropinirole hydrochloride, SmithKline Beecham brand of ropinirole hydrochloride
Sources
Derived from the NIH UMLS (Unified Medical Language System)


You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree