Neurology Book

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Beta Adrenergic Receptor

Aka: Beta Adrenergic Receptor, Beta 1 Adrenergic Receptor, Beta 2 Adrenergic Receptor
  1. See Also
    1. Adrenergic Receptor
    2. Alpha Adrenergic Receptor
    3. Sympathetic Nervous System
    4. Sympathomimetic Toxicity
    5. Sympathomimetic
  2. Beta Receptor Effects
    1. Beta Receptor General Effects
      1. Eye
        1. Relaxes Ciliary Muscle
    2. Beta 1 Receptor
      1. Myocardium
        1. Increases Myocardial Contractility
        2. Increases Heart Rate
          1. Accelerates sinoatrial node
          2. Accelerates ectopic Pacemakers
      2. Metabolic
        1. Fat Cell Lipolysis
        2. KidneyRenin Release
    3. Beta 2 Receptor
      1. Vessel
        1. Vasodilatation
      2. Lung
        1. Bronchodilation
      3. Genitourinary and Gastrointestinal
        1. Bladder wall relaxes
        2. Pregnant Uterus relaxes
      4. Metabolic
        1. Liver gluconeogenesis and glycogenolysis
  3. Medications: Beta Adrenergics
    1. Beta Adrenergic Agonist (Beta Adrenergic Receptor)
      1. Beta Non-Specific
        1. Isoproterenol
        2. Epinephrine
      2. Beta 1 Selective
        1. Norepinephrine
        2. Dobutamine
        3. Prenalterol
      3. Beta 2 Selective (See Bronchodilator)
        1. Fenoterol
        2. Albuterol
        3. Terbutaline
        4. Metaproterenol
    2. Beta Adrenergic Antagonist
      1. Beta Non-specific
        1. Propranolol
        2. Timolol
        3. Nadolol
        4. Pindolol
      2. Beta 1 Selective
        1. Metoprolol
        2. Acebutolol
        3. Alprenolol
        4. Atenolol
        5. Esmolol
      3. Beta 2 Selective
        1. Butoxamine

Receptors, Adrenergic, beta-1 (C0001642)

Definition (MSH) A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems.
Definition (NCI) Beta 1 adrenergic receptor protein (477 aa, 51 kD) is a cell communication process protein that is encoded by the human ADRB1 gene and has a role in signal transduction.
Concepts Receptor (T192) , Amino Acid, Peptide, or Protein (T116)
MSH D018342
SnomedCT 45585002
English beta-1 Adrenergic Receptors, Adrenergic Receptor, beta-1, Adrenergic Receptors, beta-1, beta 1 Adrenergic Receptors, beta-1 Adrenergic Receptor, Receptor, beta-1 Adrenergic, Receptors, beta-1 Adrenergic, Receptor, Adrenergic, beta-1, beta 1 Adrenergic Receptor, Adrenergic beta-1 Receptors, Adrenergic Receptor, beta 1, Receptors, Adrenergic beta-1, Receptors, beta 1 Adrenergic, beta-1 Receptors, Adrenergic, RECEPT ADREN BETA 1, RECEPT BETA 1 ADREN, RECEPTORS BETA 001 ADRENERGIC, ADRENERGIC RECEPTORS BETA 01, BETA 1 ADREN RECEPT, BETA ADRENERGIC RECEPTORS 01, ADREN BETA 1 RECEPT, beta-1 Adrenergic receptor site, Beta 1 Adrenergic Receptor, Receptors, Adrenergic, beta-1 [Chemical/Ingredient], Adrenergic beta 1 Receptors, beta-1 Adrenergic receptor (substance), beta-1 Adrenergic receptor, Beta 1 Receptor, Beta-1 Adrenoceptor, Beta-1 Adrenoreceptor, ADRB1, Receptors, Adrenergic, beta-1
Swedish beta-1-adrenerga receptorer
Finnish Beeta-1-adrenergiset reseptorit
Russian ADRENERGICHESKIE BETA-1 RETSEPTORY, RETSEPTORY BETA-1 ADRENERGICHESKIE, RETSEPTORY ADRENERGICHESKIE BETA-1, BETA-1 ADRENERGICHESKIE RETSEPTORY, АДРЕНЕРГИЧЕСКИЕ БЕТА-1 РЕЦЕПТОРЫ, БЕТА-1 АДРЕНЕРГИЧЕСКИЕ РЕЦЕПТОРЫ, РЕЦЕПТОРЫ АДРЕНЕРГИЧЕСКИЕ БЕТА-1, РЕЦЕПТОРЫ БЕТА-1 АДРЕНЕРГИЧЕСКИЕ
Italian Recettore beta-1 adrenergico, Recettori beta-1 adrenergici
German ADRENERGE REZEPTOREN BETA 01, REZEPTOREN BETA 001 ADRENERGE, BETA ADRENERGE REZEPTOREN 01, Adrenerge Beta-1-Rezeptoren, Beta-1-adrenerge Rezeptoren, Rezeptoren, Beta-1-adrenerge, Rezeptoren, adrenerge, Beta-1-
French Récepteur bêta-1 adrénergique, Récepteurs bêta-1 adrénergiques
Czech beta-1-adrenoreceptory, receptory adrenergní beta-1, beta-1-adrenergní receptory
Spanish Receptores Adrenérgicos beta-1, Receptores Adrenérgicos beta 1, receptor beta - 1 adrenérgico (sustancia), receptor beta - 1 adrenérgico, Receptores beta-1 Adrenérgicos
Portuguese Receptores Adrenérgicos beta-1, Receptores beta-1 Adrenérgicos, Receptores Adrenérgicos beta 1
Polish Receptory adrenergiczne beta 1
Japanese β1受容体, アドレナリンベータ1受容体, アドレナリンβ1受容体, ベータ1アドレナリンレセプター, ベータ1アドレナリン受容体, 受容体-アドレナリン作用性ベータ1, アドレナリン作用性ベータ1受容体, ベータ1受容体, 受容体-アドレナリンβ1
Sources
Derived from the NIH UMLS (Unified Medical Language System)


beta-2 Adrenergic Receptors (C0001643)

Definition (MSH) A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-2 receptors are more sensitive to EPINEPHRINE than to NOREPINEPHRINE and have a high affinity for the agonist TERBUTALINE. They are widespread, with clinically important roles in SKELETAL MUSCLE; LIVER; and vascular, bronchial, gastrointestinal, and genitourinary SMOOTH MUSCLE.
Definition (NCI) Beta 2 adrenergic receptor (413 aa, 47 kD) is a cell communication protein that is encoded by the human ADRB2 gene and has roles in endosome to lysosome transport and signal transduction.
Concepts Receptor (T192) , Amino Acid, Peptide, or Protein (T116)
MSH D018343
SnomedCT 90971001
English Adrenergic Receptor, beta-2, Adrenergic Receptors, beta-2, beta 2 Adrenergic Receptors, beta-2 Adrenergic Receptor, Receptor, beta-2 Adrenergic, Receptors, beta-2 Adrenergic, Receptor, Adrenergic, beta-2, Adrenergic beta-2 Receptors, Receptors, Adrenergic, beta-2, Adrenergic Receptor, beta 2, Receptors, Adrenergic beta-2, Receptors, beta 2 Adrenergic, beta-2 Receptors, Adrenergic, RECEPTORS BETA 002 ADRENERGIC, ADRENERGIC RECEPTORS BETA 02, RECEPTORS ADRENERGIC BETA 2, BETA 2 ADREN RECEPT, RECEPT ADREN BETA 2, BETA ADRENERGIC RECEPTORS 02, RECEPT BETA 2 ADREN, ADREN BETA 2 RECEPT, beta-2 Adrenergic receptor site, Receptors, Adrenergic, beta-2 [Chemical/Ingredient], 2 adrenergic beta receptors, beta 2 adrenergic receptors, Adrenergic beta 2 Receptors, beta-2 Adrenergic receptor (substance), beta-2 Adrenergic receptor, beta-2 Adrenergic Receptors, Catecholamine Receptor, BAR, Adrenergic, Beta-2-, Receptor, Surface, ADRB2R, ADRB2, ADRBR, B2AR, Beta-2 Adrenergic Receptor, Beta-2 Adrenoceptor, Beta-2-Adrenergic Receptor, Beta-Adrenergic Receptor
Swedish beta-2-adrenerga receptorer
Finnish Beeta-2-adrenergiset reseptorit
Russian ADRENERGICHESKIE BETA-2 RETSEPTORY, RETSEPTORY ADRENERGICHESKIE BETA-2, BETA-2 ADRENERGICHESKIE RETSEPTORY, RETSEPTORY BETA-2 ADRENERGICHESKIE, АДРЕНЕРГИЧЕСКИЕ БЕТА-2 РЕЦЕПТОРЫ, БЕТА-2 АДРЕНЕРГИЧЕСКИЕ РЕЦЕПТОРЫ, РЕЦЕПТОРЫ АДРЕНЕРГИЧЕСКИЕ БЕТА-2, РЕЦЕПТОРЫ БЕТА-2 АДРЕНЕРГИЧЕСКИЕ
Italian Recettore beta-2 adrenergico, Recettori beta-2 adrenergici
German REZEPTOREN ADRENERGE BETA 2, ADRENERGE REZEPTOREN BETA 02, BETA ADRENERGE REZEPTOREN 02, REZEPTOREN BETA 002 ADRENERGE, Adrenerge Beta-2-Rezeptoren, Beta-2-adrenerge Rezeptoren, Rezeptoren, Beta-2-adrenerge, Rezeptoren, adrenerge, Beta-2-
French Récepteurs bêta-2 adrénergiques, Récepteur bêta-2 adrénergique
Czech beta-2-adrenergní receptory, receptory adrenergní beta-2, beta-2-adrenoreceptory
Spanish Receptores Adrenérgicos beta-2, Receptores Adrenérgicos beta 2, receptor beta - 2 adrenérgico (sustancia), receptor beta - 2 adrenérgico, Receptores beta-2 Adrenérgicos
Portuguese Receptores Adrenérgicos beta-2, Receptores Adrenérgicos beta 2, Receptores beta-2 Adrenérgicos
Polish Receptory adrenergiczne beta 2
Japanese アドレナリンベータ2受容体, β2受容体, アドレナリンβ2受容体, ベータ2アドレナリンレセプタ, ベータ2アドレナリン受容体, 受容体-アドレナリン作用性ベータ2, アドレナリン作用性ベータ2受容体, ベータ2受容体, 受容体-アドレナリンβ2
Sources
Derived from the NIH UMLS (Unified Medical Language System)


beta-adrenergic receptor (C0034785)

Definition (MSH) One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.
Definition (NCI) Expressed by Beta Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI)
Definition (CSP) coupled through the G protein Gs to adenylate cyclase such that extracellular stimulation results in increased intracellular cyclic AMP; beta-1 mediates lipolysis and cardiostimulation, beta-2 broncho- and vaso- dilation.
Concepts Receptor (T192) , Amino Acid, Peptide, or Protein (T116)
MSH D011943
SnomedCT 85205004
English Adrenergic beta Receptors, beta adrenergic receptor, beta Adrenergic Receptors, Receptors, Adrenergic, beta, Receptors, beta Adrenergic, Receptor, Adrenergic, beta, Adrenergic beta-Receptors, Receptors, beta-Adrenergic, beta-Adrenergic Receptors, beta-Receptors, Adrenergic, ADRENERGIC RECEPTORS BETA, RECEPT BETA ADREN, RECEPT ADREN BETA, BETA ADREN RECEPT, ADREN BETA RECEPT, beta-Adrenergic receptor site, Beta adrenergic receptor, Receptors, Adrenergic, beta [Chemical/Ingredient], beta-adrenergic receptor, beta adrenergic receptors, adrenergic beta receptors, beta-adrenergic receptors, Beta adrenoceptors, beta-Adrenergic receptor (substance), beta-Adrenergic receptor, Beta Adrenergic Receptor
Swedish beta-adrenerga receptorer
Finnish Beeta-adrenergiset reseptorit
Russian BETA-ADRENORETSEPTORY, RETSEPTORY BETA-ADRENERGICHESKIE, ADRENERGICHESKIE BETA-RETSEPTORY, BETA-ADRENERGICHESKIE RETSEPTORY, RETSEPTORY ADRENERGICHESKIE BETA, АДРЕНЕРГИЧЕСКИЕ БЕТА-РЕЦЕПТОРЫ, БЕТА-АДРЕНЕРГИЧЕСКИЕ РЕЦЕПТОРЫ, БЕТА-АДРЕНОРЕЦЕПТОРЫ, РЕЦЕПТОРЫ АДРЕНЕРГИЧЕСКИЕ БЕТА, РЕЦЕПТОРЫ БЕТА-АДРЕНЕРГИЧЕСКИЕ
Italian Recettore beta adrenergico, Recettori beta adrenergici
German ADRENERGE REZEPTOREN BETA, Adrenerge Beta-Rezeptoren, Beta-adrenerge Rezeptoren, Rezeptoren, Beta-adrenerge, Rezeptoren, adrenerge, Beta-
Croatian RECEPTORI, ADRENERGIČKI, BETA
French Récepteurs bêta-adrénergiques
Czech beta-adrenergní receptory, receptory adrenergní beta, beta-adrenoreceptory
Polish Receptory adrenergiczne beta
Japanese アドレナリンベータ受容体, アドレナリン作用性ベータ受容体, βレセプター, β受容体, アドレナリンβ受容体, ベータアドレナリンレセプター, ベータアドレナリン受容体, ベータ受容体, 受容体-アドレナリン作用性ベータ, 受容体-アドレナリンβ
Portuguese Receptores beta Adrenérgicos, Receptores beta-Adrenérgicos, Receptores Adrenérgicos beta
Spanish Receptores beta-Adrenérgicos, Receptores Adrenérgicos beta, Receptores beta Adrenérgicos, receptor beta - adrenérgico (sustancia), receptor beta - adrenérgico
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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