Pulmonology Book

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Chronic Cough Causes

Aka: Chronic Cough Causes
  1. See Also
    1. Chronic Cough
  2. Causes: Common (represents 90% of Chronic Cough Causes)
    1. Post-nasal drainage (40%)
      1. Sinusitis
      2. Allergic Rhinitis
    2. Asthma (24%)
    3. Gastroesophageal Reflux (15%)
    4. Bronchitis or post-Bronchitic Cough (11%)
    5. Chronic Bronchitis
    6. Tobacco abuse
    7. Transient airway hyperresponsiveness
      1. Post-viral cough
      2. Post-Bronchitic cough
    8. Medication related
      1. ACE Inhibitors (5-20% of patients)
      2. Beta Blockers (less common)
    9. Infection or post-infectious cough
      1. Bordetella pertussis infection
        1. Pertussis is responsible for 20% of severe cough in adults and teens >2 weeks presenting to emergency departments
        2. Senzilet (2001) Clin Infect Dis 32:1691-7 [PubMed]
      2. Post-Bronchitic cough
  3. Causes: Less Common Causes of Chronic Cough
    1. Congestive Heart Failure
    2. Cancer
      1. Bronchogenic Carcinoma
      2. Esophageal Cancer
    3. Lung disease
      1. Emphysema
      2. Sarcoidosis
      3. Bronchiectasis (4%)
      4. Eosinophilic Bronchitis
      5. Tuberculosis
      6. Fungal Lung Infection
      7. Cystic Fibrosis
    4. Recurrent Aspiration
      1. Post-Cerebrovascular Accident
      2. Frequent Vomiting
      3. Alcoholism
    5. Pressure from an intrathoracic mass
      1. Thoracic aneurysm
      2. Thyromegaly
      3. Mediastinal Lymphadenopathy
    6. Irritation of cough receptors in ear
      1. Impacted cerumen or hair in ear canal
      2. Hair
      3. Ear Foreign Body
    7. Opportunistic infections (immunocompromised patient)
    8. Lymphangitis carcinomatosis
    9. Foreign body
    10. Chronic occupational inhalation Bronchial irritants
    11. Psychogenic cough (Habit Cough)
    12. Arteriovenous malformation
  4. References
    1. Benich (2011) Am Fam Physician 84(8): 887-92 [PubMed]
    2. Palombini (1999) Chest 116:279-84 [PubMed]
    3. Irwin (2000) N Engl J Med 343:1715-21 [PubMed]

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