Pulmonology Book

http://www.fpnotebook.com/

Delta F508

Aka: Delta F508
  1. Indications
    1. Suspected false negative Sweat Test in Cystic Fibrosis
    2. Predict severity of Cystic Fibrosis
    3. Determine Cystic Fibrosis carrier status of siblings
  2. Method
    1. Identifies Chromosome 7 mutation
      1. Associated with 70% of Cystic Fibrosis
    2. Obtain cheek epithelial cells

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