Infectious Disease Book

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Herpes Simplex Virus

Aka: Herpes Simplex Virus, Simplexvirus
  1. See Also
    1. Herpes Virus
  2. Types
    1. Oral Herpes
    2. Genital Herpes
    3. Neonatal Herpes Simplex Virus
  3. Complications
    1. Herpes Keratitis (Corneal infection)
    2. Herpetic Whitlow (painful vesicular lesions on fingers)
    3. Herpetic sycosis (beard area vesicular eruption)
    4. Herpes gladiatorum (vesicular lesions typically on torso with history of wrestling exposure)
    5. Erythema Multiforme (HSV is the most common cause)
    6. HSV Encephalitis
  4. Labs: Diagnosis
    1. See HSV Test
  5. References
    1. Colgan (2003) Am Fam Physician 67(4):757-62 [PubMed]
    2. Usatine (2010) Am Fam Physician 82(9):1075-82 [PubMed]

Herpes Simplex Infections (C0019348)

Definition (MEDLINEPLUS)

Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted disease (STD). It affects the genitals, buttocks or anal area. Other herpes infections can affect the eyes, skin, or other parts of the body. The virus can be dangerous in newborn babies or in people with weak immune systems.

There are two types of HSV:

  • HSV type 1 most commonly causes cold sores. It can also cause genital herpes.
  • HSV type 2 is the usual cause of genital herpes, but it also can infect the mouth.

HSV spreads direct contact. Some people have no symptoms. Others get sores near the area where the virus has entered the body. They turn into blisters, become itchy and painful, and then heal.

Most people have outbreaks several times a year. Over time, you get them less often. Medicines to help your body fight the virus can help lessen symptoms and decrease outbreaks.

Definition (MSH) A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
Definition (CSP) infection caused by the herpes simplex virus; affects the skin and nervous system; produces small temporary (but sometimes painful) blisters on the skin and mucous membranes.
Concepts Disease or Syndrome (T047)
MSH D006561
ICD9 054
ICD10 B00, B00.9
SnomedCT 186534002, 154332007, 266191005, 88594005
English Herpes Simplex, Herpes simplex disease, HERPES SIMPLEX, Herpesvirus hominis disease, herpes simplex virus infection, infection due to Herpes simplex virus, infection due to Herpes simplex virus (diagnosis), Herpes simplex NOS, Herpesviral [herpes simplex] infections, Herpes simplex infection NOS, Herpes Simplex [Disease/Finding], herpes simplex infection, herpes infections simplex, simplex herpes, diseases herpes simplex, infection herpes simplex, herpes simplex, HSV, Simplex - herpes, Herpes simplex, Herpes simplex infection, Herpes simplex viral infection, Herpes simplex (disorder), herpes; simplex, simplex; herpes, Herpes simplex, NOS, HSV infection, Herpes Simplex Infections, Herpes simplex complex
Portuguese HERPES SIMPLES, Infecção por VHS, Herpes simples NE, Herpes Recorrente, Herpes simples, Herpes Simples
Spanish HERPES SIMPLE, Infección por VHS, Herpes simplex NEOM, Herpes simplex, Herpes Recurrente, herpes catarral, herpes facial, herpes febril, herpes simple (trastorno), herpes simplex, herpes simple, infección por virus Herpes simplex, Herpes Simple
German HERPES SIMPLEX, HSV-Infektion, Herpes simplex NNB, Infektionen durch Herpesviren [Herpes simplex], Herpes simplex
Dutch HSV-infectie, herpes simplex NAO, herpes; simplex, simplex; herpes, herpes simplex, Herpesvirus-infecties [herpes simplex], Herpes simplex
French Herpes simplex SAI, Infection à VHS (virus Herpès simplex), Infections au VHS, Infections au virus de l'herpès simplex, HERPES SIMPLE, Herpès
Italian Herpes simplex NAS, Infezione da herpes virus simplex, Herpes simplex
Japanese 単純ヘルペスNOS, HSV感染, 単純ヘルペス, HSVカンセン, タンジュンヘルペスNOS, タンジュンヘルペス
Swedish Herpes simplex
Czech herpes simplex, Infekce HSV, Herpes simplex NOS, Herpes simplex, opar
Finnish Yskänrokko
Russian GERPES PROSTOI, ГЕРПЕС ПРОСТОЙ
Korean 헤르페스바이러스[단순 헤르페스] 감염
Croatian HERPES SIMPLEKS
Polish Opryszczka pospolita, Opryszczka zwykła
Hungarian HSV fertőzés, herpes simplex k.m.n., herpes simplex
Norwegian Herpes simplex
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Simplexvirus (C0206558)

Definition (NCI) HSV is a nuclear replicating, icosahedral, enveloped DNA virus. The HSV envelope contains at least 8 glycoproteins. The matrix or tegument which contacts both the envelope and the capsid contains at least 15-20 proteins. There are two types of HSV - Type 1 and Type 2. The Type 1 virus causes cold sores. Most people get Type 1 infections during infancy or childhood. The Type 2 virus causes genital sores. Most people get Type 2 infections following sexual contact with an infected person.
Definition (NCI_NCI-GLOSS) A type of virus that causes herpes infections and has DNA as its genetic material. There are two types of herpes simplex viruses. Infections with type 1 viruses cause cold sores on the lips or nostrils. Infections with type 2 viruses cause sores on the genitals (external and internal sex organs and glands).
Definition (NCI_CDISC) Any viral organism that can be assigned to the species Human Herpesvirus 1 within the genus Simplexvirus.
Definition (MSH) A genus of the family HERPESVIRIDAE, subfamily ALPHAHERPESVIRINAE, consisting of herpes simplex-like viruses. The type species is HERPESVIRUS 1, HUMAN.
Concepts Virus (T005)
MSH D018139
SnomedCT 314797000, 19965007, 243575004, 243574000, 48832003
LNC LP21270-1, LP14558-8
English Herpes labialis Virus, Herpes labialis Viruses, Herpes Simplex Virus, Herpes Simplex Viruses, Herpesvirus hominis, Simplexviruses, Genus: Human herpesvirus 1 group, Genus: Human herpesvirus 1 grp, Human herpesvirus 1 group virus, Human herpesvirus 1 grp virus, Genus Simplexvirus, human herpesvirus 1 group, simplex virus herpes, labialis herpes virus, simplexvirus, herpes simplex viruses, herpes virus simplex, hsv, Human Herpesvirus 1, Herpes simplex group virus, Herpes simplex virus group, Simplexvirus (living organism) (organism), Human herpesvirus 1 group virus (organism), Herpes simplex group virus (organism), herpes simplex virus, Herpes Simplex Virus 1, HHV1, HHV-1, HUMAN HERPESVIRUS 1, HSV-1, Herpes Simplex Virus type 1, HSV1, HSV, human herpesvirus, HHV, Herpesvirus, Herpes simplex virus, HSV - Herpes simplex virus, HS - Herpes simplex, Simplexvirus, Genus Simplexvirus (organism), herpesvirus, Herpes simplex virus group, NOS, Herpesvirus, NOS, Simplexvirus, NOS, Simplexvirus (living organism) [Ambiguous], Simplexvirus (organism)
Dutch HSV, Herpes-labialis-virus, Herpes-simplex-virus, Herpesvirus hominis, Virus, simplex-
French HSV, Simplexvirus, Herpes labialis virus, Herpes simplex virus, Virus de l'herpès de la lèvre, Virus de l'herpès labial, Virus de l'herpès simplex, Virus de l'herpès, Herpesvirus hominis
German HSV, Herpes-labialis-Virus, Herpes-simplex-Virus, Herpesvirus hominis, Simplexvirus
Italian Virus dell'Herpes simplex, Virus dell'herpes labiale, Virus dell’herpes simplex, Simplexvirus
Portuguese Vírus de herpes simples, Herpesvirus dos Platirrinos, Herpesvirus hominis, Simplexvirus, Vírus do Herpes Labial, Vírus do Herpes Simplex
Spanish VMS, género Simplexvirus, virus simplex, Simplexvirus, virus del grupo del virus 1 del herpes humano, virus del grupo herpes simplex, grupo del virus del herpes simple, virus del grupo del hepes simple (organismo), virus del grupo del virus 1 del herpes humano (organismo), simplexvirus, género: grupo 1 del herpes humano, virus del grupo del hepes simple, simplexvirus (organismo vivo), Virus del Tití, Herpesvirus de los Platirrinos, simplexvirus (concepto no activo), virus simplex (organismo), género Simplexvirus (organismo), Herpesvirus hominis, Virus Herpes Labialis, Virus Herpes Simplex
Japanese 超選択的迷走神経切断術, チョウセンタクテキメイソウシンケイセツダンジュツ, キヌザルヘルペスウイルス, 単純ウイルス, ヘルペスウイルス1-リスザル, Saimirineヘルペスウイルス1(アルファ), 広鼻猿類ヘルペスウイルス, シンプレックスウイルス属, リスザルヘルペスウイルス1型, リスザルヘルペスウイルス1, ヘルペスウイルス1型-リスザル, 単純疱疹ウイルス, ヘルペスウイルス1(アルファ)-リスザル, マーモセットウイルス, 口唇ヘルペスウイルス, Saimirineヘルペスウイルス1, 単純ヘルペスウイルス
Swedish Simplexvirus
Czech Simplexvirus, HSV
Finnish Simplex-virus
Russian MARMOZETOK VIRUS, GERPESVIRUS PLOSKONOSYKH OBEZ'IAN, GERPESVIRUS 1 SAIMIRI, GERPESVIRUS 1 (AL'FA) SAIMIRI, GERPESA GUB VIRUS, GERPESVIRUS CHELOVECHESKII, GERPESA PROSTOGO VIRUS, SIMPLEXVIRUS, ГЕРПЕСА ГУБ ВИРУС, ГЕРПЕСА ПРОСТОГО ВИРУС, ГЕРПЕСВИРУС 1 (АЛЬФА) САЙМИРИ, ГЕРПЕСВИРУС 1 САЙМИРИ, ГЕРПЕСВИРУС ПЛОСКОНОСЫХ ОБЕЗЬЯН, ГЕРПЕСВИРУС ЧЕЛОВЕЧЕСКИЙ, МАРМОЗЕТОК ВИРУС
Polish Herpesvirus platyrrhnae, Wirusy herpes simplex, Herpesvirus hominis, Wirusy pazurczatek, Wirus opryszczki pospolitej
Hungarian Superselectiv vagotomia
Croatian Not Translated[Simplexvirus]
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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