Hematology and Oncology Book

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G6PD Deficiency Detection

Aka: G6PD Deficiency Detection, G6PD Activity
  1. See Also
    1. G6PD Deficiency
  2. Indications for testing
    1. Acute or chronic non-spherocytic Hemolytic Anemia
    2. Asymptomatic children with significant risk factors
    3. Nonphysiologic Neonatal Jaundice with risk factors
    4. Associated risk factors
      1. African, Mediterranean, or Asian ethnicity
      2. Family History of Jaundice, Anemia or Splenomegaly
  3. Detection Methods
    1. Quantitative analysis
    2. Rapid fluorescent Spot Test
      1. Detects NADPH generation
  4. False negatives
    1. Acute Hemolytic Anemia
    2. Female Heterozygotes

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