Gynecology Book

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Sentinel Node Breast Biopsy

Aka: Sentinel Node Breast Biopsy
  1. Indications
    1. Breast Cancer Staging
  2. Advantages
    1. Much less invasive than axillary node dissection
  3. Technique
    1. Albumin labeled with technetium-99m injected
    2. Scanning times
      1. Fifteen minutes
      2. Thirty minutes
      3. Three hours
    3. Sentinel Node appears first or most radioactive
  4. Efficacy: Sentinel Node versus Axillary node dissection
    1. Studied 160 Italian women ages 25-77 years
    2. Focal tumors 5-6 cm in diameter
      1. Sensitivity: 95%
      2. Positive Predictive Value: 97%
      3. Missed 5 cases
        1. Micrometastases
        2. Multifocal tumors
    3. Choose appropriate patients for this technique
    4. Reference
      1. Veronesi (1997) Lancet 349:1864-7 [PubMed]

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