Gynecology Book

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Loestrin 1.5/30

Aka: Loestrin 1.5/30, Loestrin 30, Microgestin 1.5/30, Junel 1.5/30
  1. See Also
    1. Oral Contraceptive
    2. Oral Contraceptive Drug Interaction
    3. Oral Contraceptive Selection
    4. Oral Contraceptive Side Effect Management
    5. Oral Contraceptive-Related Uterine Bleeding Management
  2. Preparations (Norethindrone Acetate 1500 mcg / Ethinyl Estradiol 30 mcg)
    1. Loestrin 1.5 / 30
    2. Loestrin 30 (UK)
    3. Microgestin 1.5/30
    4. Junel 1.5/30
  3. Components
    1. Norethindrone Acetate 1500 mcg (see preparation above)
    2. Ethinyl Estradiol 30 ug
  4. Effects
    1. Relative Progestational Activity: 1.7 (high)
    2. Estrogenic Activity: 14 (low)
    3. Androgenic Activity: 0.80 (high)
  5. Pill associated problems
    1. Indications to switch to Ortho Cyclen
      1. Acne Vulgaris (lower androgen)
      2. Increased Appetite (lower Progestin)
      3. Major Depression provoked (lower Progestin)
      4. Moodiness (less Estrogen or more Progestin)
      5. Weight gain (less Estrogen or more Progestin)
    2. Indications to switch to Loestrin 1/20
      1. Breast Tenderness or engorgement (lower Estrogen)
      2. Headaches (lower Estrogen)
    3. Indications to switch to Nordette
      1. Libido decreased (more androgen)
      2. Break-through bleed days 1-9 (more Estrogen)
      3. Break-through bleed all of month (more Estrogen)
      4. Menses too light (more Estrogen, less Progestin)
    4. Indications to switch to Ortho Novum 777
      1. Heavy Menses (more Progestin or less Estrogen)
      2. Dysmenorrhea or Menstrual Cramps (more Progestin)
      3. Break-through bleed days 10-21 (more Progestin)
  6. References
    1. Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
    2. Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
    3. Dickey (1998) Managing Contraceptive Pill Patients

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