Gynecology Book

http://www.fpnotebook.com/

Breast Cancer Staging

Aka: Breast Cancer Staging
  1. Stages
    1. Stage 1
      1. Tumor <=2 cm with no lymph node metastasis
    2. Stage 2
      1. Tumor >2 cm or positive lymph nodes
    3. Stage 3
      1. Locally advanced Breast Cancer (Skin or Chest wall)
    4. Stage 4
      1. Metastatic Breast Cancer (Lung, Liver, Bones, Brain)
  2. Prognosis
    1. Stage 1:
      1. Five year survival: 90%
    2. Stage 2
      1. Five year survival: <60%
      2. Seven Year survival
        1. One to three nodes positive: 60%
        2. Over 3 nodes positive: 38%
    3. Reference:
      1. (1988) NIH Publication No. 88-2789
      2. Fisher (1983) Cancer 52:1551-7 [PubMed]
  3. Methods
    1. Sentinel Node Breast Biopsy
      1. Recommended even in favorable Breast Cancer subtypes
        1. Wong (2002) Am J Surg 184:492-8 [PubMed]
    2. Axillary Node dissection
      1. Conventional staging procedure
      2. Complications
        1. Numbness in axillae
        2. Hand and arm Lymphedema (may be severe)

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