Gastroenterology Book

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Loperamide

Aka: Loperamide, Imodium
  1. See Also
    1. Loperamide Toxicity
  2. Indications
    1. See Loperamide Misuse
    2. Traveler's Diarrhea
  3. Mechanism
    1. Peripherally acting Opioid
  4. Dosing
    1. Initial: 4 mg PO for single first dose
    2. Titrate: 2 mg PO after each loose stool
    3. Maximum: 16 mg/day
Medication Costs
loperamide (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
LOPERAMIDE 1 MG/5 ML LIQUID Generic OTC $0.02 per ml
LOPERAMIDE 1 MG/7.5 ML LIQUID Generic OTC $0.02 per ml
LOPERAMIDE 1 MG/7.5 ML SUSP Generic OTC $0.02 per ml
LOPERAMIDE 2 MG CAPSULE Generic $0.28 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Loperamide (C0023992)

Definition (NCI) A synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastro-intestinal motility by effects on the circular and longitudinal muscles of the intestine. Part of its anti-diarrheal effect may be due to a reduction of gastro-intestinal secretion produced by opioid receptor binding in the intestinal mucosa. (NCI04)
Definition (MSH) One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D008139
SnomedCT 116726003, 387040009
LNC LP18991-7, MTHU007262
English Loperamide, 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, loperamide, Loperamide [Chemical/Ingredient], LOPERAMIDE, Loperamide (product), Loperamide (substance)
Swedish Loperamid
Czech loperamid
Finnish Loperamidi
Russian LOPERAMID, LOPERAMIDGIDROKHLORID, ЛОПЕРАМИД, ЛОПЕРАМИДГИДРОХЛОРИД
Japanese カグダリン, ロペナ, ロンバニン, ベルテッサ, ロスポリア, ロペミン, ロペラニール, ロペラン, ミロピン, クラレット, ロペカルド, タイペミン, ロペミック, ロペラミド, 塩酸ロペラミド, ロペジャスト, ロペラミド塩酸塩
Polish Loperamid
Spanish loperamida (producto), loperamida (sustancia), loperamida, Loperamida
French Lopéramide
German Loperamid
Italian Loperamide
Portuguese Loperamida
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Imodium (C0591635)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D008139
English imodium, Imodium
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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