Gastroenterology Book

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Pancreatitis Causes

Aka: Pancreatitis Causes
  1. See Also
    1. Pancreatitis
    2. Medication Causes of Pancreatitis
  2. Causes: Most common
    1. Adults
      1. Alcohol Abuse (35% of cases)
      2. Cholelithiasis (40% of cases)
    2. Children
      1. Infection (e.g. Mumps, Viral Hepatitis, Coxsackievirus, Ascariasis, Mycoplasma)
      2. Abdominal Trauma (e.g. handlebar injury)
  3. Causes: Gastrointestinal
    1. Abdominal Trauma or surgery
    2. Following Endoscopic Retrograde Cholangiopancreatography (ERCP)
    3. Peptic Ulcer perforation
    4. Hereditary Pancreatitis
    5. Pancreas divisum
    6. Ampulla of Vater Obstructed (e.g. Regional Enteritis)
    7. Sphincter of odi dysfunction
    8. Abdominal Trauma (1.5% of cases)
  4. Causes: Endocrine
    1. Hypertriglyceridemia (may be related to Diabetes Mellitus)
    2. Hypercalcemia (e.g. hypervitaminosis D, Hyperparathyroidism, Total Parenteral Nutrition)
    3. Renal Failure
    4. Cystic Fibrosis (Chronic Pancreatitis)
    5. Hemochromatosis (Chronic Pancreatitis)
  5. Causes: Infection
    1. Mumps
    2. Viral Hepatitis
    3. Coxsackievirus
    4. Ascariasis
    5. Mycoplasma
  6. Causes: Medications and toxins
    1. See Medication Causes of Pancreatitis
    2. Accounts for 2% of cases
    3. Toxins include Snake Bites and Scorpion bites
  7. Causes: Vasculitis
    1. Systemic Lupus Erythematosus (SLE)
    2. Necrotizing angiitis
    3. Thrombotic Thrombocytopenic Purpura (TTP)
  8. References
    1. Mitchell (2003) Lancet 361:1447-55 [PubMed]
    2. Swaroop (2004) JAMA 291:2865-8 [PubMed]
    3. Tenner (2004) Am J Gastroenterol 99:2489-94 [PubMed]
    4. Quinlan (2014) Am Fam Physician 90(9): 632-9 [PubMed]

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