Gastroenterology Book

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Hepatitis D

Aka: Hepatitis D, Delta Agent
  1. See Also
    1. Viral Hepatitis
    2. Hepatitis B
  2. Epidemiology
    1. Endemic Hepatitis B
      1. Mediterranean basin
      2. South America
    2. Percutaneous spread via Intravenous Drug Abuse
    3. Transfusion (e.g. Hemophilia)
  3. Pathophysiology
    1. Defective 37 nm RNA virus
    2. Requires Hepatitis BVirus for replication
    3. Enhances severity of Hepatitis B infection
    4. Transmission
      1. Coinfection with Hepatitis B
      2. Superinfection of a Hepatitis B Carrier
  4. Differential Diagnosis
    1. Acute Hepatitis Causes
  5. Labs
    1. Hepatitis D Serology (xHDV)
      1. Higher titers suggest chronic Hepatitis D
  6. Management
    1. See Chronic Hepatitis B Infection
  7. Complications
    1. Fulminant Hepatitis
    2. Chronic Hepatitis
    3. Cirrhosis
  8. Prevention
    1. Hepatitis B Vaccine for Non-Carriers of Hepatitis B

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