Gastroenterology Book

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Ranson Criteria

Aka: Ranson Criteria, Pancreatitis Prognosis
  1. See Also
    1. Acute Pancreatitis
    2. BALI Score
    3. BISAP Score
    4. Revised Atlanta Criteria for Acute Pancreatitis Severity
    5. CT Severity Index in Pancreatitis (Balthazar Computed Tomography Severity Index)
    6. Acute Physiology and Chronic Health Evaluation II (APACHE II Score)
    7. Modified Glasgow Severity Criteria for Pancreatitis (Imrie Scoring System for Pancreatitis, PANCREAS Score)
  2. Indication
    1. Predicts prognosis in Acute Pancreatitis
    2. Initially derived from Alcoholic Pancreatitis
      1. Prognosis is better for other types of Pancreatitis
  3. Criteria: Admission Risk Factors
    1. Age over 55 years old
    2. Blood Glucose >200
    3. Serum Lactate Dehydrogenase (LDH) >300
    4. Aspartate Aminotransferase (AST, SGOT) >250
    5. White Blood Cell Count >16,0000
  4. Criteria: At 48 hours Risk Factors
    1. Hematocrit falls >10%
    2. Blood Urea Nitrogen (BUN) increased >5 mg/dl
    3. Serum Calcium <8.0
    4. Arterial PO2 <60
    5. Base Deficit >4
    6. Estimated fluid sequestration >6L
  5. Interpretation
    1. Risk factors <3: 1% mortality
    2. Risk factors 3-4: 15% mortality
    3. Risk factors 5-6: 40% mortality
    4. Risk factors >7: 100% mortality
  6. Efficacy
    1. Test Sensitivity for predicting poor outcome: 70%
  7. References
    1. Ranson (1974) Surg Gynecol Obstet 139(1): 69-81 [PubMed]

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