Ophthalmology Book

http://www.fpnotebook.com/

Topical Eye Antibiotic

Aka: Topical Eye Antibiotic, Ophthalmic Antibiotic
  1. Indications
    1. Treatment of infection
      1. Bacterial Conjunctivitis
    2. Prophylaxis in Eye Injury (avoid Aminoglycosides due to toxicity risk)
      1. Corneal Abrasion
      2. Chemical Eye Burn
  2. Preparations: Most cost effective agents
    1. First-line
      1. Trimethoprim-Polymyxin B (Polytrim) solution
      2. Erythromycin 0.5% ointment
    2. Broad-spectrum
      1. Gentamicin (Gentak) 0.3% ointment or solution
      2. Tobramycin (Tobrex) 0.3% solution (ointment is not generic and is expensive)
      3. Ciprofloxacin (Ciloxan) 0.3% ointment or solution
      4. Ofloxacin (Ocuflox) 0.3% solution
  3. Preparations: First-Line general purpose
    1. Trimethoprim-Polymyxin B (Polytrim) solution
    2. Sulfacetamide 10% (Bleph-10) ointment or Solution
      1. Typically avoid due to low efficacy and reaction risk
  4. Preparations: First-Line Macrolides (especially if Chlamydia suspected)
    1. Erythromycin 0.5% ointment
    2. Azithromycin 1% (Azasite) solution
    3. Bacitracin ointment (used in stye)
  5. Preparations: Broad-Spectrum Fluoroquinolones
    1. Precautions
      1. Reserve for severe infections to prevent resistance
    2. Besifloxacin (Besivance) 0.6% solution
    3. Ciprofloxacin (Ciloxan) 0.3% ointment or solution
    4. Gatifloxacin (Zymar) 0.3%
    5. Levofloxacin (Iquix) 1.5% or (Quixin) 0.5% solution
    6. Moxifloxacin (Vigamox) 0.5% solution
    7. Ofloxacin (Ocuflox) 0.3% solution
  6. Preparations: Broad-spectrum Aminoglycosides
    1. Precautions
      1. Reserve for severe infections to prevent resistance
      2. Avoid if Corneal Injury (toxicity risk)
    2. Gentamicin (Gentak) 0.3% ointment or solution
    3. Tobramycin (Tobrex) 0.3% ointment or solution
  7. Preparations: To Avoid
    1. Neomycin (topical reactions are common)
  8. References
    1. Cronau (2010) Am Fam Physician 81(2): 137-45 [PubMed]

You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree