Endocrinology Book

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Medications Associated with Unintentional Weight Loss

Aka: Medications Associated with Unintentional Weight Loss, Unintentional Weight Loss due to Medications, Drug Induced Unintentional Weight Loss
  1. See Also
    1. Unintentional Weight Loss
    2. Unintentional Weight Loss Causes
  2. Mechanisms
    1. Altered taste or smell
      1. See Drug-Induced Gustatory Dysfunction (includes Drug-Induced Olfactory Dysfunction)
      2. Allopurinol
      3. ACE Inhibitors
      4. Calcium Channel Blockers
      5. Levodopa
      6. Propranolol
      7. Spironolactone (Aldactone)
    2. Dry Mouth
      1. See Medication Causes of Dry Mouth
      2. Anticholinergic Medications (e.g. Antihistamines)
      3. Clonidine (Catapres)
      4. Loop Diuretics
    3. Anorexia (medications suppressing appetite)
      1. Anticonvulsants (e.g. Topiramate)
      2. Appetite Suppressants (e.g. Phentermine)
      3. Bupropion (Wellbutrin)
      4. Levodopa
      5. Metformin (Glucophage)
      6. Opioid Analgesics
      7. Stimulant Medications (e.g. Methylphenidate, Dextroamphetamine)
      8. Theophylline
    4. Dysphagia
      1. See Pill Esophagitis
      2. Bisphosphonates
      3. Doxycycline
      4. Iron Supplementation
      5. NSAIDs
      6. Potassium Supplementation
    5. Nausea or Vomiting
      1. See Medication Induced Vomiting
      2. Amantadine
      3. Digoxin
      4. Dopamine Agonists
      5. Metformin
      6. Selective Serotonin Reuptake Inhibitor (SSRI)
      7. Tricyclic Antidepressants
  3. Causes: Cardiopulmonary Agents
    1. Beta Blockers (common)
    2. Central alpha antagonists (common)
    3. Loop Diuretics (common)
    4. Albuterol
    5. ACE Inhibitors
    6. Calcium Channel Blockers
    7. Digoxin
    8. AntiHyperlipidemic medications
    9. Transdermal Nitroglycerin
  4. Causes: Neuropsychiatric Preparations
    1. Anticholinergic Medications (common)
    2. Anticonvulsants, e.g. Phenytoin (common)
    3. Benzodiazepines (common)
    4. Neuroleptic agents (common)
    5. Selective Serotonin Reuptake Inhibitors, SSRI (common)
    6. Tricyclic Antidepressants (common)
    7. Dopamine Agonists (e.g. Levodopa)
  5. Causes: Endocrine Preparations
    1. Corticosteroids (common)
    2. Alendronate
    3. Hormonal Medications
    4. Metformin
  6. Causes: Rheumatologic Preparations
    1. Allopurinol
    2. NSAIDs
    3. Opioid Analgesics
  7. Causes: Infectious Disease Preparations
    1. Antibiotics
    2. Amantadine
    3. Metronidazole
  8. Causes: Miscellaneous Preparations
    1. Antihistamines
    2. Decongestants
    3. Iron Supplements
    4. Potassium
    5. Xanthines
  9. References
    1. Gaddey (2014) Am Fam Physician 89(9):718-22 [PubMed]
    2. Huffman (2002) Am Fam Physician 65(4):640-50 [PubMed]
    3. Verdery (1997) Clin Geriatr Med 13:769-78 [PubMed]

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