Endocrinology Book

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Lorcaserin

Aka: Lorcaserin, Belviq, Belviq XR
  1. See Also
    1. Medications Associated with Weight Gain
    2. Orlistat (Xenical)
    3. Phentermine (Ionamin, Fastin)
    4. Phentermine and Topiramate (Qsymia, Qnexa)
    5. Obesity
    6. Obesity in Children
    7. Obesity Evaluation
    8. Obesity Measurement (or Obesity Screening)
    9. Obesity Risk (or Obesity Comorbid Conditions)
    10. Obesity Management
    11. Obesity Medication
    12. Dietary Supplements in Obesity
    13. Exercise in Obesity
    14. Obesity Resources
  2. Background
    1. Released in U.S. in 2013
  3. Efficacy
    1. Weight loss is 7 pounds more than Placebo in one year
    2. Weight loss of at least 5% in up to 47% of patients at one year
  4. Mechanism
    1. Serotonin 2C agonist that increases satiety
  5. Dosing
    1. Lorcaserin (Belviq) 10 mg orally twice daily
    2. Belviq XR preparation available for once daily use in 2017
    3. Stop medication if 5% weight loss is not achieved at 12 weeks
  6. Adverse Effects
    1. Well tolerated
    2. More specific, and does not appear to carry same valvular heart disease risks as with fenfluramine
    3. Constipation
    4. Cough
    5. Dry Mouth
    6. Fatigue
    7. Nausea
    8. Hypoglycemia
  7. Drug Interactions
    1. Serotonergic medications (e.g. SSRI, Dextromethorphan)
      1. Serotonin Syndrome risk
  8. References
    1. (2013) Presc Lett 20(7): 37
    2. Erlandson (2016) Am Fam Physician 94(5): 361-8 [PubMed]
    3. Fidler (2011) J Clin Endocrinol Metab 96:3067-3077 [PubMed]
Medication Costs
belviq (on 9/8/2016 at Medicaid.Gov Pharmacy Drug pricing)
BELVIQ 10 MG TABLET $3.89 each
BELVIQ XR 20 MG TABLET $7.73 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

lorcaserin (C2350948)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C506658
English Lorcaserin, (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, lorcaserin, LORCASERIN
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Belviq (C3485407)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C506658
English Belviq
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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