Otolaryngology Book

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Rhinitis Medicamentosa

Aka: Rhinitis Medicamentosa
  1. Pathophysiology
    1. Associated with topical agent use >5-7 days
    2. Tachyphylaxis associated with medications
      1. Nasal Decongestants (Afrin, Neo-Synephrine)
      2. Nasal spray preservative Benzalkonium chloride
    3. Other associated medications
      1. Reserpine
      2. Oral Contraceptive pills
      3. Inderal
      4. Aldomet
  2. Symptoms
    1. Rebound nasal Congestion after nasal Decongestant
  3. Signs
    1. Fiery red edema at nasal mucosa
  4. Management
    1. Intranasal Steroid (e.g. Vancenase)
    2. Withdrawal of nasal Decongestant
  5. Prevention
    1. Avoid prolonged use of nasal Decongestants
  6. Reference
    1. Graf (1997) J Allergy 52(40 suppl): 28-34 [PubMed]

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