Otolaryngology Book

http://www.fpnotebook.com/

Acute Generalized Exanthematous Pustulosis

Aka: Acute Generalized Exanthematous Pustulosis, AGEP
  1. See Also
    1. Life-Threatening Drug-Induced Rashes
    2. Adverse Drug Reaction
    3. Hypersensitivity Reaction
    4. Anaphylaxis
    5. Penicillin Allergy
    6. Gell and Coombs Classification
    7. Fixed Drug Eruption
  2. Pathophysiology
    1. Adverse Drug Reaction
  3. Symptoms
    1. Rash onset within four days of offending medication exposure
  4. Signs
    1. Fever
    2. Rash
      1. Onset at flexor surfaces (e.g. neck, axilla, antecubital fossa, popliteal fossa)
      2. Tiny, non-follicular Pustules
  5. Causes
    1. Beta-lactam antibiotics (Penicillins, Cephalosporins, carbapenems)
    2. Macrolide antibiotics (e.g. Erythromycin, Azithromycin)
    3. Calcium Channel Blockers
  6. Labs
    1. Complete Blood Count
      1. Leukocytosis
      2. Neutrophilia
  7. Management
    1. Eliminate the offending agent
    2. Consider Topical Corticosteroids
  8. References
    1. Jhun and DeClerck in Herbert (2015) EM:Rap 15(2): 9-11

You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree