Dermatology Book

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Azelaic Acid

Aka: Azelaic Acid, Azelex
  1. See Also
    1. Acne Vulgaris Pharmacologic Management
  2. Indication
    1. Acne Vulgaris
  3. Mechanism
    1. Topical antibacterial, Keratolytic agent
  4. Efficacy
    1. Not as effective as originally thought
    2. Only mild effect
    3. Use as an adjunct to other treatment
  5. Dosing
    1. Apply twice daily
    2. Cream 20% (Azelex)
      1. Approved for Acne Vulgaris
    3. Gel 15% (Finacea)
      1. Approved for Acne Rosacea
      2. Much better bioavailability than Azelex
  6. Adverse Effects
    1. Hypopigmentation
    2. Less irritating than Tretinoin or Benzoyl Peroxide
    3. Pruritus
    4. Burning, stinging and tingling
    5. Local erythema
  7. Precautions
    1. Use caution in Acne Vulgaris patients with dark skin
    2. May cause Hypopigmentation
  8. Safety
    1. Pregnancy Category B
      1. Only category B Keratolytic agent
Medication Costs
azelex (on 2/22/2017 at Medicaid.Gov Pharmacy Drug pricing)
AZELEX 20% CREAM $12.04 per gram
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Azelex (C0718755)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C010038
English Azelex, azelex
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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