Dermatology Book

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Anthralin

Aka: Anthralin
  1. Indication
    1. Psoriasis
  2. Dosing
    1. Use alone or in combination with UV light
    2. Should be used only by experienced practitioner
  3. Side Effects
    1. Irritation
    2. Stains clothing

Anthralin (C0003166)

Definition (NCI) A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04)
Definition (MSH) An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D000875
SnomedCT 387293003, 332227001, 53800008
English 1,8 Dihydroxy 9 anthrone, 1,8,9-Anthracenetriol, 1,8-Dihydroxy-9-anthrone, Anthralin, Dihydroxyanthranol, Dithranol, 1,8-Dihydroxy-9(10H)-anthracenone, DIHYDROXYANTHRONE 010809, Dithranol [generic additions], anthralin preparations, anthralin preparations (medication), Anthralin [Chemical/Ingredient], anthralin, ANTHRALIN, dithranol, Dithranol [generic additions] (product), Anthralin (product), Anthralin (substance), Dithranol [generic additions] (substance)
Swedish Antralin
Czech anthralin
Finnish Ditranoli
Russian DITRANOL, ANTRALIN, АНТРАЛИН, ДИТРАНОЛ
Japanese アントラリン, アンスラリン, 1,8-ジヒドロキシ-9-アントロン, ジトラノール
German DIHYDROXYANTHRON 010809, 1,8-Dihydroxy-9-Anthron, Anthralin, Dithranol
Croatian ANTRALIN
Polish Antralina, Ditranol
Spanish 1,8-Dihidroxi-9-antrona, ditranol (agregados genéricos), ditranol (agregados genéricos) (producto), antralina (producto), antralina (sustancia), antralina, Antralina, Ditranol
Portuguese 1,8-Di-Hidroxi-9-antrona, Antralina, Ditranol
French Dithranol
Italian Antralina
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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