Cardiovascular Medicine Book

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Labetalol

Aka: Labetalol, Trandate
  1. See Also
    1. Alpha Adrenergic Antagonist
    2. Beta Blocker
  2. Indications
    1. Refractory Hypertension
      1. Very effective outpatient agent in oral form patients with Refractory Hypertension
    2. Hypertensive Emergency
      1. Nicardipine has replaced intravenous Labetalol for Hypertensive Emergency
        1. Difficult to achieve Blood Pressure control in Hypertensive Crisis despite titration
        2. Short acting
      2. Labetalol is a preferred agent when compared with Hydaralazine and Clonidine
  3. Mechanism
    1. Combination of classes
      1. Alpha Adrenergic Antagonist and
      2. Nonselective Beta Blocker
    2. Primary activity is as a negative inotrope
      1. Chronotropic effect is mild
  4. Dosing
    1. Oral: 100 mg PO bid (Maximum: 2400 mg/day)
    2. Intravenous: 20 mg IV q10 minutes (Maximum: 200 mg)
Medication Costs
labetalol (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
LABETALOL HCL 100 MG TABLET Generic $0.22 each
LABETALOL HCL 200 MG TABLET Generic $0.26 each
LABETALOL HCL 300 MG TABLET Generic $0.47 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

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