Cardiovascular Medicine Book

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Intravenous Antihypertensive

Aka: Intravenous Antihypertensive
  1. Preparations: Calcium Channel Blockers
    1. Nicardipine
  2. Preparations: Direct Acting Vasodilators IV
    1. Hydralazine (Apresoline)
      1. Dose: 10-40 mg IV/IM q4-6h
    2. Diazoxide (Hyperstat)
      1. Dose: 1-3 mg/kg up to 150 mg IV q5-15 min
    3. NitroprussideSodium (Nipride)
    4. Nitroglycerin Drip
  3. Preparations: Beta Blockers IV
    1. Esmolol (Brevibloc)
      1. Half-life: 9 minutes
      2. Preparation: 5g in 500 ml (10 mg/ml)
      3. Load: 500 ug/kg over 1 minute (70 kg: 35 mg, 3.5 ml)
      4. Infusion: 50-200 ug/kg/min IV (70 kg: 40 ml/h)
    2. Labetalol (Trandate)
      1. Start: 20 mg IV
      2. Titrate: 40-80 mg every 10 min up to 300 mg
    3. Metoprolol (Lopressor)
      1. Start: 5 mg increments IV
      2. Titrate: 5 mg IV q5-15 minutes to maximum of 15 mg
  4. Preparations: ACE Inhibitors IV
    1. Enalapril (Vasotec)
      1. Dose: 1.25 mg IV q6h

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