I. Indications: Anemia Evaluation

  1. Iron Deficiency Anemia from other Microcytic Anemias
  2. May increase before MCV becomes abnormal

II. Definition

  1. Measures size variability of Red Blood Cell population

III. Normal

  1. Range: 11.5-14.5%

V. Increased Red Cell Distribution Width (RDW)

  1. Mean Corpuscular Volume (MCV) Increased
    1. Vitamin B12 Deficiency
    2. Folate Deficiency
    3. Immune Hemolytic Anemia
    4. Liver disease
  2. Mean Corpuscular Volume (MCV) Normal
    1. RDW increases before MCV becomes abnormal
      1. Early Iron Deficiency Anemia
      2. Early Vitamin B12 Deficiency
      3. Early Folate Deficiency
    2. Anemic globinopathy
  3. Mean Corpuscular Volume (MCV) Decreased
    1. Iron Deficiency Anemia
    2. RBC fragmentation
    3. HbH
    4. Thalassemia intermedia

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Ontology: Red cell distribution width determination (C0427460)

Definition (NCI) An index of the variation in the size of the red cells and can be used to detect subtle degress of anisocytosis. It is computed directly from the RBC histogram and is calculated as a standard statictical value, the coefficient of variation of the red cell volume ditribution (ratio of standard deviation and mean copuscular volume).
Definition (NCI) A value derived from mean corpuscular volume and the standard deviation of the red blood cell volume in a whole blood specimen.
Concepts Laboratory Procedure (T059)
SnomedCT 143103004, 250229004, 165701004, 66842004
Italian Ampiezza di distribuzione del volume eritrocitario
Japanese 赤血球分布幅, セッケッキュウブンプハバ
English Erythrocyte Distribution Width Measurement, RDW, Red blood cell distribution width (& level) (procedure), Red blood cell distribution width (observable entity), Erythrocytes Distribution Width, Erythrocyte distribution width, cells distribution red width, red cell distribution width, red cell width distribution, cell distribution red width, Red cell distribution width, RDW determination, RDW - Red blood cell distribution width, Red cell distribution width determination (procedure), Red blood cell distribution width, Red blood cell distribution width (& level), Red cell distribution width determination
Spanish Red blood cell distribution width (& level), Red blood cell distribution width, determinación de la ESD, determinación de la VSG, determinación de la eritrosedimentación (procedimiento), determinación de la eritrosedimentación, determinación de la velocidad de sedimentación globular, Rango de volumen eritrocitario
Czech Distribuční šíře erytrocytů
Hungarian Vörössejt megoszlási spektrum
Portuguese Amplitude de distribuição de eritrócitos
Dutch rode cel distributiebreedte
French Espace de distribution des cellules rouges
German Verteilungsmuster der Erythrozyten