Hematology and Oncology Book

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Hemoglobin

Aka: Hemoglobin, Hgb, Hemoglobin Cutoffs for Anemia
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  1. Interpretation: Normal Values per age (-2 to +2 S.D)
    1. Birth: 13.5 to 24.0 g/dl (mean 16.5 g/dl)
    2. Age <1 month: 10.0 to 20.0 g/dl (mean 13.9 g/dl)
    3. Age 1-2 months: 10.0 to 18.0 g/dl (mean 11.2 g/dl)
    4. Age 2-6 months: 9.5 to 14.0 g/dl (mean 12.6 g/dl)
    5. Age 0.5 to 2 years: 10.5 to 13.5 g/dl (mean 12.0 g/dl)
    6. Age 2 to 6 years: 11.5 to 13.5 g/dl (mean 12.5 g/dl)
    7. Age 6-12 years: 11.5 to 15.5 g/dl (mean 13.5)
    8. Female
      1. Age 12-18 years: 12.0 to 16.0 g/dl (mean 14.0 g/dl)
      2. Age >18 years: 12.1 to 15.1 g/dl (mean 14.0 g/dl)
    9. Male
      1. Age 12-18 years: 13.0 to 16.0 g/dl (mean 14.5 g/dl)
      2. Age >18 years: 13.6 to 17.7 g/dl (mean 15.5 g/dl)
  2. Interpretation: Anemia Cut-offs
    1. Men
      1. Age 12-14 years: <12.5 g/dl (CDC)
      2. Age 15-17 years: <13.3 g/dl (CDC)
      3. Age >17 years: <13 g/dl (WHO) or <13.5 g/dl (CDC)
    2. Women (Non-pregnant, non-lactating)
      1. Age 12-14 years: <11.8 g/dl
      2. Age 15-17 years: <12.0 g/dl
      3. Age >17 years: <12 g/dl (WHO and CDC)
    3. Women in Pregnancy (CDC Guidelines <5th percentile)
      1. First Trimester: <11.0 g/dl
      2. Second Trimester: <10.5 g/dl
      3. Third Trimester: <11.0 g/dl
    4. Children (CDC Guidelines <5th percentile)
      1. Age 1-2 years: <11.0 g/dl
      2. Age 2-5 years: <11.1 g/dl
      3. Age 5-8 years: <11.5 g/dl
      4. Age 8-11 years: <11.9 g/dl
    5. Infants (2 S.D. below mean)
      1. Term (cord blood): <13.5 g/dl (mean 16.5 g/dl)
      2. Newborn (1-3 days): <14.5 g/dl (mean 18.5 g/dl)
      3. Age 2 weeks: <13.4 g/dl (mean 16.6 g/dl)
      4. Age 1 month: <10.7 g/dl (mean 13.9 g/dl)
      5. Age 2 months: <9.4 g/dl (mean 11.2 g/dl)
      6. Age 6 months: <11.1 g/dl (mean 12.6 g/dl)
  3. Increased Hemoglobin
    1. Polycythemia Vera
    2. Vigorous Exercise
    3. High altitude
  4. Decreased Hemoglobin
    1. See Anemia
  5. References
    1. Behrman (2000) Nelson Pediatrics, Saunders, p. 1462
    2. Johnson (1993) Harriet Lane Handbook, Mosby, p. 231
    3. (1998) MMWR Morb Mortal Wkly Rep 47:1-29
      1. http://www.cdc.gov/mmwr/pdf/rr/rr4703.pdf

Hemoglobinopathies (C0019045)

Definition (NCI) An inherited disorder characterized by structural alterations of a globin chain within the hemoglobin molecule.
Definition (MSH) A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
Definition (CSP) group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
Concepts Disease or Syndrome (T047)
MSH D006453
ICD10 D58.2
SnomedCT 80141007, 154794008, 267556002
English Hemoglobinopathies, hemoglobinopathies, Globin abnormality, NOS, HEMOGLOBINOPATHIES, Hemoglobin disease, NOS, Hemoglobin disorder, NOS, Hemoglobinopathy, NOS, Haemoglobin disease, NOS, Haemoglobin disorder, NOS, Haemoglobinopathy, NOS, Hemoglobinopathy NOS, hemoglobin disorders, HEMOGLOBIN DISORDER, hemoglobinopathy, hemoglobinopathy (diagnosis), C-20 HEMOGLOBINOPATHIES, Haemoglobinopathies congenital, Haemoglobinopathies, Haemoglobinopathy NOS, HEMOGLOBINOPATHY, Hemoglobinopathies [Disease/Finding], Hemoglobin disorders, haemoglobin disease, haemoglobinopathies, hemoglobin disease, hemoglobin disorder, diseases hemoglobin, disorders hemoglobin, haemoglobinopathy, Hemoglobin disease, Hemoglobinopathy, Hemoglobin disorder, Haemoglobinopathy, Globin abnormality, Haemoglobin disease, Haemoglobin disorder, Hemoglobinopathy (disorder), Hemoglobinopathies / Iron Metabolism, Hemoglobinopathies congenital
Italian Emoglobinopatia, Emoglobinopatie congenite, Emoglobinopatia NAS, Emoglobinopatie
Dutch hemoglobinopathie NAO, hemoglobinopathie, hemoglobinopathieën, congenitaal, hemoglobinopathieën, Hemoglobinopathie, Hemoglobinopathieën
French Hémoglobinopathie SAI, Hémoglobinopathie, Hémoglobinopathies congénitales, Hémoglobinopathies, Maladies de l'hémoglobine
German Haemoglobinopathie NNB, Haemoglobinopathien, Haemoglobinopathie, Kongenitale Haemoglobinopathien, Hämoglobinopathien
Portuguese Hemoglobinopatia NE, Hemoglobinopatias congénitas, Hemoglobinopatia, Hemoglobinopatias
Spanish Hemoglobinopatía NEOM, Haemoglobinopathy, Hemoglobinopathy, alteración de la hemoglobina, hemoglobinopatía (trastorno), hemoglobinopatía, trastorno de la hemoglobina, Hemoglobinopatías congénitas, Hemoglobinopatía, Hemoglobinopatias, Hemoglobinopatías
Japanese 異常ヘモグロビン症ＮＯＳ, 先天性異常ヘモグロビン症, 異常ヘモグロビン症, ｲｼﾞｮｳﾍﾓｸﾞﾛﾋﾞﾝｼｮｳ, ｲｼﾞｮｳﾍﾓｸﾞﾛﾋﾞﾝｼｮｳNOS, ｾﾝﾃﾝｾｲｲｼﾞｮｳﾍﾓｸﾞﾛﾋﾞﾝｼｮｳ
Swedish Hemoglobinopatier
Czech hemoglobinopatie, Hemoglobinopatie, Vrozené hemoglobinopatie, Hemoglobinopatie NOS, Patologie hemoglobinu
Finnish Hemoglobinopatiat
Russian GEMOGLOBINOPATII, ГЕМОГЛОБИНОПАТИИ
Croatian HEMOGLOBINOPATIJE
Polish Hemoglobinopatie
Hungarian Haemoglobinopathiák, veleszületett, Haemoglobinopathia, Haemoglobinopathiák, Haemoglobinopathia k.m.n., Hemoglobinopatia
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Hemoglobin measurement (C0518015)

Definition (NCI) A measurement of the hemoglobin in a biological specimen.
Definition (NCI) A quantitative measurement of the amount of hemoglobin present in a sample.
Concepts Laboratory Procedure (T059)
SnomedCT 35170002
CPT 85018
English Hemoglobin, Hemoglobin determination, Hemoglobin determination, NOS, HEMOGLOBIN, Haemoglobin, Haem, Haemoglobin determination, NOS, HGB, Hemoglobin Measurement, Hemoglobin measurement, hemoglobin, Haemoglobin determination, Hemoglobin determination (procedure), hemoglobin measurement (lab test), hemoglobin measurement, hemoglobin testing, Test;haemoglobin, hemoglobin tests, haemoglobin tests, test hemoglobin, Blood count; hemoglobin (Hgb), BLOOD COUNT; HEMOGLOBIN (HGB), BLD# HGB, Test;hemoglobin, haemoglobin test, hemoglobin test
Italian Emoglobina, Eme
Dutch haemoglobine, haem, hemoglobine
French Hémorr, Hémoglobine
German Haem, Haemoglobin
Portuguese Heme, Hemoglobina
Spanish Hemo, determinación de Hb, determinación de hemoglobina, determinación de hemoglobina (procedimiento), hemoglobina, Hemoglobina
Japanese ヘモグロビン, ﾍﾓｸﾞﾛﾋﾞﾝ
Czech Hem, Hemoglobin
Hungarian Haem, Haemoglobin, Hemoglobin
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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