II. Definition

  1. Cancer arrising in mesenchymal (connective) tissue
  2. Derived from greek word "sar" meaning fleshy

III. Types

  1. Soft-tissue Sarcomas
    1. Kaposi's Sarcoma
    2. Hepatic angiosarcoma
    3. Rhabdomyosarcoma
      1. Most common soft tissue Sarcoma in children
    4. Leiomyosarcoma
      1. Involves Uterus in adults
      2. Involves Retroperitoneum in children
    5. Liposarcoma
      1. Rare adipose tumor (usually invades locally only)
      2. Involves deep thigh or Retroperitoneum
    6. Fibrosarcoma
      1. Most common soft tissue Sarcoma in age <1 year
      2. Involves deep thigh or Retroperitoneum
  2. Vascular Sarcoma
    1. Angiosarcoma
    2. Hemangioendothelioma
    3. Hemangiopericytoma
  3. Bone tumors
    1. Ewing's Sarcoma
    2. Osteogenic Sarcoma

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Ontology: Sarcoma (C1261473)

Definition (MSHCZE) Obecné označení pro zhoubný nádor z pojivové tkáně (vazivo, chrupavka, kost), krvetvorné a lymfatické tkáně či svalu. Podle tkáně původu se také nazývá: název tkáně (resp. nezhoubného nádoru) se doplní koncovkou -sarkom (fibrom – fibrosarkom, myom – myosarkom, lipom – liposarkom, hemangiom – hemangiosarkom, osteom – osteosarkom). S. patří u lidí k vzácnějším nádorům (na rozdíl od některých zvířat) – častější jsou karcinomy. (cit. Velký lékařský slovník online, 2012 http://lekarske.slovniky.cz/ )
Definition (MEDLINEPLUS)

Your soft tissues connect, support, or surround other tissues. Examples include your muscles, tendons, fat, and blood vessels. Soft tissue sarcoma is a cancer of these soft tissues. There are many kinds, based on the type of tissue they started in. They may cause a lump or swelling in the soft tissue. Sometimes they spread and can press on nerves and organs, causing problems such as pain or trouble breathing.

No one knows exactly what causes these cancers. They are not common, but you have a higher risk if you have been exposed to certain chemicals, have had radiation therapy, or have certain genetic diseases.

Doctors diagnose soft tissue sarcomas with a biopsy. Treatments include surgery to remove the tumor, radiation therapy, chemotherapy, or a combination.

NIH: National Cancer Institute

Definition (NCI_NCI-GLOSS) A cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue.
Definition (NCI) A malignant mesenchymal tumor for which a distinct line of differentiation cannot be determined. This term may be used for small biopsy specimens for which adequate tissue is not present for definitive classification.
Definition (NCI) A usually aggressive malignant mesenchymal cell tumor most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The prognosis depends largely on the degree of differentiation (grade) of the tumor. Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma.
Definition (NCI_CDISC) A malignant mesenchymal neoplasm. A general term for which the transformed cell type has not been specified.
Definition (NCI) A malignant mesenchymal neoplasm arising exclusively from the soft tissues. Representative examples include soft tissue sarcoma, extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumor, and malignant hemangiopericytoma.
Definition (NCI) A malignant mesenchymal neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones.
Definition (MSH) A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Definition (CSP) any of a group of tumors usually arising from connective tissue, although the term now includes some of epithelial origin; most are malignant.
Concepts Neoplastic Process (T191)
MSH D012509
ICD10 M8800/3
SnomedCT 424952003, 424413001, 93765001, 2424003, 269634000, 363362006, 189764008, 269469005
French SARCOME, Sarcome SAI, Cancer des tissus mous, Tumeur maligne des tissus mous SAI, Tumeur maligne des tissus mous, Sarcome des tissus mous, Sarcome, Sarcomes
English Sarcoma, Soft Tissue, Sarcomas, Soft Tissue, Soft Tissue Sarcomas, Malig tumor of soft tissue, Malig tumour of soft tissue, Sarcoma of the Soft Tissue and Bone, Sarcoma of soft tissue, Sarcoma (disorder), Sarcoma of soft tissue (disorder), Soft tissue sarcomas, [M]Sarcoma NOS, Malignant neop of soft tissue, Sarcoma NOS, Malignant neoplasm of soft tissues, malignant neoplasm of soft tissue, sarcoma of soft tissue, sarcoma (diagnosis), sarcoma, malignant neoplasm of soft tissue (diagnosis), sarcoma of soft tissue (diagnosis), Sarcoma, no ICD-O subtype, malignant soft tissue neoplasm, malignant tumor of soft tissue, Sarcoma [Disease/Finding], Sarcoma, malignant soft tissue tumors, sarcomas soft tissue, cancer of the soft tissue, mesenchymal malignant tumor, sarcomas, soft tissue sarcomas, sarcoma soft tissue, soft tissue sarcoma, Soft Tissue Sarcoma, Soft tissue cancer, Malignant soft tissue neoplasm, Malignant soft tissue neoplasm NOS, Malignant tumor of soft tissue (disorder), [M]Sarcoma NOS (morphologic abnormality), Sarcoma, no International Classification of Diseases for Oncology subtype (morphologic abnormality), Sarcoma, no ICD-O subtype (morphologic abnormality), Sarcoma, no International Classification of Diseases for Oncology subtype, SARCOMA OF THE SOFT TISSUE AND BONE, Non-Rhabdo. soft tissue sarcoma, SARCOMA, SARCOMA, MALIGNANT, Non-Rhabdomyosarcoma soft tissue sarcoma, NOS, MESENCHYMAL TUMOR, MALIGNANT, SARCOMA OF SOFT TISSUE AND BONE, Soft tissue tumor, malignant, Mesenchymal tumor, malignant, Malignant mesenchymal tumor, Malignant mesenchymal tumour, Malignant tumor of soft tissue, Malignant tumour of soft tissue, Soft tissue sarcoma, Mesenchymal tumour, malignant, Soft tissue tumour, malignant, Malignant neoplasm of soft tissue, Malignant neoplasm of soft tissue (disorder), sarcoma; soft tissue, soft tissue; sarcoma, Sarcoma, NOS, Sarcomas, Connective Tissue Sarcoma, Malignant Neoplasm of Soft Tissue, Malignant Neoplasm of the Soft Tissue, Malignant Soft Tissue Neoplasm, Malignant Soft Tissue Tumor, Malignant Tumor of Soft Tissue, Malignant Tumor of the Soft Tissue, Sarcoma of Soft Tissue and Bone, Sarcoma of Soft Tissue, Sarcoma of the Soft Tissue, Neoplasm malig;soft tissue, malignant neosplasm of the soft tissue
Portuguese SARCOMA, Sarcoma NE, Neoplasia maligna dos tecidos moles NE, Neoplasia maligna dos tecidos moles, Cancro dos tecidos moles, Sarcoma de Tecidos Moles, Sarcoma
Spanish SARCOMA, Sarcoma NEOM, sarcoma de partes blandas (trastorno), sarcoma, sarcoma de partes blandas, sarcoma (trastorno), Neoplasia maligna de tejidos blandos NEOM, Cáncer de tejidos blandos, Neoplasia maligna de tejidos blandos, tumor maligno de partes blandas (trastorno), [M]sarcoma, SAI, [M]sarcoma, SAI (anomalía morfológica), morfología: sarcoma, no clasificado como subtipo en CIE - O (anomalía morfológica), neoplasia maligna de partes blandas (trastorno), neoplasia maligna de partes blandas, tumor maligno de partes blandas, tumor mesenquimatoso maligno, tumor mesenquimático maligno, morfología: sarcoma, no clasificado como subtipo en CIE - O, neoplasia maligno de partes blandas (trastorno), neoplasia maligno de partes blandas, Sarcoma, Sarcoma de Tejidos Blandos
German SARKOM, Sarkom NNB, boesartige Neubildung der Weichteile NNB, Weichteilkrebs, boesartige Neubildung der Weichteile, Sarkom, Weichteil-, Sarkom
Dutch sarcoom NAO, wekedelentumor, wekedelenneoplasma maligne NAO, wekedelenneoplasma maligne, sarcoom; weke delen, weke delen; sarcoom, sarcoom, Sarcoom, Sarcoom, wekedelen-
Italian Sarcoma NAS, Sarcoma dei tessuti molli, Cancro del tessuto molle, Tumore maligno dei tessuti molli NAS, Tumore maligno dei tessuti molli, Sarcoma
Japanese 肉腫NOS, ニクシュ, ニクシュNOS, 肉腫-類上皮, 紡錘細胞肉腫, 類上皮肉腫, 肉腫, 紡錘形細胞肉腫, 肉腫-紡錘細胞, 軟部組織癌, ナンブソシキガン, 軟部組織の悪性新生物, ナンブソシキノアクセイシンセイブツNOS, 軟部組織の悪性新生物NOS, ナンブソシキノアクセイシンセイブツ
Swedish Sarkom
Czech sarkom, Sarkom, Sarkom NOS, sarkomy měkkých tkání, sarkom měkkých tkání, Rakovina měkké tkáně, Maligní novotvar měkké tkáně NOS, Maligní novotvar měkké tkáně
Finnish Sarkooma
Russian SARKOMA, SARKOMA EPITELIOIDNAIA, SARKOMA MIAGKIKH TKANEI, SARKOMA VERETENOKLETOCHNAIA, САРКОМА, САРКОМА ВЕРЕТЕНОКЛЕТОЧНАЯ, САРКОМА МЯГКИХ ТКАНЕЙ, САРКОМА ЭПИТЕЛИОИДНАЯ
Croatian SARKOM
Polish Mięsak
Hungarian Sarcoma, Sarcoma k.m.n., Lágyszövet-rák, Rosszindulatú lágyrész neoplasia k.m.n., Rosszindulatú lágyrész neoplasia
Norwegian Sarkom, Bløtvevssarkom