II. Causes: Hypertrichosis (non-androgen related)

  1. Cyclosporine - common
  2. Acitretin (Soriatane)
  3. Azelaic Acid (Finacea)
  4. Cetirizine (Zyrtec)
  5. Citalopram (Celexa)
  6. Topical Corticosteroids
  7. Diazoxide
  8. Etonogestrel Implant (Implanon)
  9. Penicillamine
  10. Phenytoin (Dylantin)
  11. Streptomycin
  12. Minoxidil

III. Causes: Hirsutism (related to excessive androgen exposure)

  1. Endocrine agents
    1. Systemic Corticosteroids
    2. Sex Hormones
      1. Anabolic Steroids
      2. Danazol (Danocrine)
      3. Testosterone
      4. Estrogens
      5. Leuprolide (Lupron)
      6. Progestins
    3. Oral Contraceptives: High Progestin Androgenic Activity
      1. Levonorgestrel (Nordette, Alesse, Triphasil)
      2. Norethindrone (Loestrin, Estrostep, Ortho Novum 1/35)
      3. Norgestrel (e.g. Ovral, Lo-Ovral, Ovrette)
  2. Chemotherapeutic and Immunosuppressant agents
    1. Cyclosporine
    2. Interferon alfa
    3. Mycophenolate (Cellcept)
    4. Tacrolimus (Prograf)
  3. Cardiovascular agents
    1. Reserpine (Serpasil)
    2. Methyldopa (Aldomet)
  4. Dermatologic agents
    1. Isoretinoin (Accutane)
  5. Gastrointestinal agents
    1. Metoclopramide (Reglan)
    2. Phenothiazines
  6. Psychiatric agents
    1. Aripiprazole (Abilify)
    2. Bupropion (Wellbutrin)
    3. Clonazepam (Klonopin)
    4. Eszopiclone (Lunesta)
    5. Fluoxetine (Prozac)
    6. Olanzapine (Zyprexa)
    7. Paroxetine (Paxil)
    8. Trazodone
    9. Venlafaxine (Effexor)
  7. Neurologic Agents
    1. Carbamazepine (Tegretol)
    2. Lamotrigine (Lamictal)
    3. Dantrolene
    4. Diazoxide
    5. Pregabalin (Lyrica)
    6. Selegeline (Eldepryl)
    7. Tiagabine (Gabitril)
    8. Zonisamide (Zonegran)
  8. Ophthalmologic Agents
    1. Bimatoprost (Lumigan)

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Ontology: Hirsutism (C0019572)

Definition (NCI_CTCAE) A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen).
Definition (NCI) Male-pattern hair growth on a female.(NICHD)
Definition (MSH) A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.
Definition (CSP) excess hair in females and children with an adult male pattern of distribution.
Concepts Finding (T033)
MSH D006628
ICD9 704.1
ICD10 L68.0
SnomedCT 40090008, 399939002
English Hirsutism, HIRSUTISM, Excessive growth of hair, Excessive hair growth, Hairiness, hirsutism, excessive facial or body hair (symptom), hirsutism (diagnosis), excessive facial or body hair (hirsutism), excessive facial or body hair, Hirsutism [Disease/Finding], hypertrichosis, polytrichia, excessive hairiness, excessive growth hair, hairiness, excessive growth of hair, excessive hair growth, pilosis, hirsuitism, hirsute, Hirsuitism, Hirsutism (disorder), Hirsuties, Pilosis, Hirsutes, Hirsutism, NOS
French HIRSUTISME, Pilosité, Hirsutisme
Portuguese HIRSUTISMO, Pilosidade, Hirsutismo
Spanish HIRSUTISMO, Vellosidad, crecimiento excesivo del pelo (trastorno), crecimiento excesivo del pelo, pilosis, hirsutismo (trastorno), hirsutismo, Hirsutismo
German HIRSUTISMUS, Hirsuitismus, Behaartheit, Hirsutismus
Dutch behaardheid, hirsutisme, Hirsutisme
Italian Villosità, Pelosità anormale, Irsutismo
Japanese 男性型多毛症, ダンセイガタタモウショウ
Swedish Hårighet, patologisk
Czech hirzutismus, Hirsutismus, Zvýšené ochlupení, nadměrné ochlupení, hirsutizmus
Finnish Hirsutismi
Russian GIRSUTIZM, ГИРСУТИЗМ
Korean 털과다증
Croatian HIRZUTIZAM
Polish Hirsutyzm
Hungarian Szőrösség, Hirsutismus, túlzott szőrnövekedés
Norwegian Unormal hårvekst, Hirsutisme, Hårvekst, unormal

Ontology: Hypertrichosis (C0020555)

Definition (NCI) Excessive hair growth anywhere on the body.
Definition (NCI_CTCAE) A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race.
Definition (MSH) Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.
Concepts Disease or Syndrome (T047)
MSH D006983
ICD10 L68 , L68.3, L68.9
SnomedCT 156409007, 201164001, 40090008, 201165000, 29966009, 271607001
English Hypertrichoses, Hypertrichosis, HYPERTRICHOSIS, Hypertrichosis, unspecified, hypertrichosis (diagnosis), hypertrichosis, excess hair, Hypertrichosis [Disease/Finding], excessive hairiness, polytrichia (diagnosis), hypertrichosis polytrichia, polytrichia, Hypertrichosis NOS (disorder), Pilosis, Excessive hair growth (disorder), Polytrichia, Excessive hair growth, Hirsutism - hypertrichosis, Excessive hairiness, Excessive hair growth (finding), Hypertrichiasis, Hypertrichosis (disorder), Polytrichosis, Excessive growth of hair, Hairiness, excessive; hair growth, Hypertrichiasis, NOS, Hypertrichosis, NOS, Polytrichia, NOS, Polytrichosis, NOS, Hypertrichosis NOS
French HYPERTRICHOSE, Hypertrichoses, Hypertrichose
Portuguese HIPERTRICOSE, Hipertricoses, Hipertricose
Spanish HIPERTRICOSIS, hipertricosis, SAI (trastorno), hipertricosis, SAI, crecimiento excesivo de cabello (hallazgo), crecimiento excesivo de cabello, hipertricosis (trastorno), hipertricosis, hipertriquiasis, politricosis, politriquia, Trastornos hipertricósicos, Hipertricosis
German HYPERTRICHOSE, Hypertrichose, nicht naeher bezeichnet, Polytrichie, Hypertrichosen, Hypertrichose
Italian Politricosi, Ipertricosi
Japanese 多毛症, タモウショウ
Swedish Hypertrikos
Czech hypertrichóza, Hypertrichóza, Hypertrichózy
Finnish Hypertrikoosi
Russian GIPERTRIKHOZ, ГИПЕРТРИХОЗ
Korean 상세불명의 털과다증, 털과다증
Polish Owłosienie nadmierne
Hungarian Hypertrichosisok, Hypertrichosis
Norwegian Hypertrikose
Dutch overmatig; haargroei, Hypertrichose, niet gespecificeerd, Polytrichose, hypertrichose, overvloedige haargroei, Hypertrichose, Trichose, hyper-

Ontology: Hyperandrogenism (C0206081)

Definition (MSH) A condition caused by the excessive secretion of ANDROGENS from the ADRENAL CORTEX; the OVARIES; or the TESTES. The clinical significance in males is negligible. In women, the common manifestations are HIRSUTISM and VIRILISM as seen in patients with POLYCYSTIC OVARY SYNDROME and ADRENOCORTICAL HYPERFUNCTION.
Concepts Disease or Syndrome (T047)
MSH D017588
SnomedCT 237793004
English Hyperandrogenism, Hyperandrogenism [Disease/Finding], hyperandrogenism, Hyperandrogenisation syndrome, Hyperandrogenization syndrome (disorder), Hyperandrogenization syndrome
Dutch hyperandrogenisme, Androgenisme, hyper-, Hyperandrogenisme
French Hyperandrogénisme, Hyperandrogénie
Japanese アンドロゲン過剰症, アンドロゲンカジョウショウ
Swedish Hyperandrogenism
Czech hyperandrogenismus, Hyperandrogenismus
Finnish Hyperandrogenismi
Russian GIPERANDROGENIZM, ГИПЕРАНДРОГЕНИЗМ
Polish Hiperandrogenizm
Hungarian Hyperandrogenismus
Norwegian Hyperandrogenisme
Spanish hiperandrogenismo, síndrome de hiperandrogenización (trastorno), síndrome de hiperandrogenización, Hiperandrogenismo
German Hyperandrogenismus
Italian Iperandrogenismo
Portuguese Hiperandrogenismo