II. Physiology

  1. Normal ovulatory cycles are 21-35 days in duration
  2. Normal cycles typically vary by only 1-2 days per month

III. History: Suggesting Ovulation

  1. Keep a menstrual Diary for several months
    1. Record days of uterine bleeding and amount
    2. Record associated symptoms
  2. Document premenstrual and Menstrual Symptoms
    1. Breast tenderness
    2. Menstrual Cramps
    3. Depressed mood
    4. Mid-cycle pelvic cramping (Mittelschmerz)

IV. Signs: Basal Body Temperature (BBT)

  1. Basal Body Temperature increase of 0.3 to 1.0 F
  2. Inaccurate method
    1. Ovulation could occur 6 days before BBT nadir
    2. Ovulation could occur 4 days after BBT nadir

V. Labs: Indications of Ovulation (most accurate testing)

  1. Mid-Luteal Serum Progesterone Level (Day 21)
    1. Level >5.0 ng/ml (15.9 nmol/L) suggests Ovulation
    2. Level <4.0 ng/ml suggests Anovulation
  2. Morning Urine LH surge testing
    1. Urine LH surge occurs 72 hours before Ovulation

VI. Efficacy: Ineffective methods of determining Ovulation

  1. Salivary Ferning
  2. Salivary B-glucuronidase activity

VII. Efficacy: Prediction of fertile window

  1. Prediction inaccurate in most women
  2. Days 6-21: 10% probability each day of fertile window

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Ontology: Ovulation (C0029965)

Definition (NCI) The discharge of a secondary oocyte from a vesicular follicle of the ovary.
Definition (NCI_NCI-GLOSS) The release of an egg from an ovary during the menstrual cycle.
Definition (CSP) discharge of an ovum from a vesicular follicle of the ovary.
Definition (MSH) The discharge of an OVUM from a rupturing follicle in the OVARY.
Definition (GO) The release of a mature ovum/oocyte from an ovary. [GOC:bf, ISBN:0878932437]
Concepts Organ or Tissue Function (T042)
MSH D010060
SnomedCT 34008004
English Ovulation, Ovulations, Ovulation, function, ovulate, ovulation, ovulations, ovulates, ovulating, Release of Egg, Ovulation, function (observable entity), Ovulation (function)
Swedish Ägglossning
Czech ovulace
Finnish Ovulaatio
Russian OVULIATSIIA, ОВУЛЯЦИЯ
Croatian OVULACIJA
Polish Jajeczkowanie, Owulacja
Norwegian Eggløsning
Spanish ovulación (entidad observable), ovulación (función), ovulación, Ovulación
French Ovulation
German Ovulation
Italian Ovulazione
Dutch Ovulatie
Portuguese Ovulação