I. Indications

II. Dose

  1. Adults: 40-125 mg po qid
  2. Infants: 0.3 ml PO qid prn

III. Pharmacokinetics

  1. Not absorbed

IV. Efficacy

  1. Several controlled clinical trials have been performed
  2. No evidence that Simethicone is better than Placebo

Images: Related links to external sites (from Google)

Cost: Medications

Gas-X Extra Strength (on 2/9/2012 at DrugStore.com)
Gas-X Extra Strength 18 125mg Chew Tabs Box #1 for $17.59 ($17.59/unit)

Ontology: Simethicone (C0037138)

Definition (MSH) A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base.
Definition (NCI) A mixture of polydimethylsiloxanes with antifoaming and anti-bloating effects. Simethicone reduces the surface tension of gas bubbles causing them to coalesce into larger bubbles that can be passed more easily by belching or flatulence.
Concepts Organic Chemical (T109) , Pharmacologic Substance(T121) , Biomedical or Dental Material(T122)
MSH D012841
SnomedCT 387442005, 77898008
English simethicone, Simeticone, Simethicone, simethicone (medication), Simethicone [Chemical/Ingredient], dimethicone activated, activated dimethicone, Activated dimethicone, Activated methylpolysiloxane, Simethicone (product), Simethicone (substance), SIMETHICONE
Swedish Simetikon
Czech simethikon
Finnish Simetikoni
Japanese シメチコン
Spanish dimeticona, dimeticona activada, metilpolisiloxano activado, simeticona (producto), simeticona (sustancia), simeticona, Simeticona
Polish Dimetykon
French Siméthicone
German Simethicon
Italian Simeticone
Portuguese Simeticone

Ontology: Mylicon (C0721886)

Concepts Organic Chemical (T109) , Pharmacologic Substance(T121)
English Mylicon, mylicon

Ontology: Phazyme (C0722576)

Concepts Organic Chemical (T109) , Pharmacologic Substance(T121)
English Phazyme, phazymes, phazyme