II. Epidemiology

  1. Rare in non-developed countries
  2. Prevalence
    1. Age over 45 years: 5-10%
    2. Age over 85 years: 80%

III. Pathophysiology

  1. Characteristics
    1. Colonic muscle wall is weak where vessels penetrate
    2. Usually multiple Diverticuli present
    3. Size: Usually <10 mm
  2. Distribution
    1. Sigmoid colon
      1. Most common site for Diverticuli in western societies (accounts for 85% of Diverticuli)
    2. Ascending colon (right Diverticuli)
      1. Age <60 years
      2. Asian patients
  3. Protective factors
    1. Vegetarian diet
    2. High fiber diet

IV. Symptoms

  1. Asymptomatic in 85% of patients
  2. Colicky Abdominal Pain without inflammation in 15%
    1. Relieved with Bowel Movement or flatus
    2. Worse with eating
    3. Associated with bloating and Constipation
    4. Left lower abdominal tenderness to palpation
  3. Diverticulitis develops in 5% of patients

VI. Diagnosis: Symptomatic Diverticular Disease

  1. Colonoscopy is test of choice
    1. Rules out Colon Cancer
    2. Contraindicated in active Diverticulitis

VII. Management

  1. High fiber diet
  2. Avoid high residue foods (seeds, nuts, corn)
    1. Recommended theoretically to prevent lodging in tics
    2. No evidence to support this
  3. Antispasmodic agents have no evidence to support use

VIII. Complications

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Ontology: Diverticulosis (C1510475)

Definition (MSH) A condition characterized by the presence of multiple diverticuli in the walls of an organ.
Definition (NCI_NCI-GLOSS) A condition marked by small sacs or pouches in the walls of a hollow organ, such as the colon. These sacs can become inflamed and cause a condition called diverticulitis.
Definition (NCI) A finding indicating the presence of multiple pouches, usually in the colonic or gastric wall.
Concepts Anatomical Abnormality (T190) , Disease or Syndrome (T047)
MSH D004240
ICD9 562
ICD10 K57 , K57.90
SnomedCT 68047000, 155778008, 197094004, 235772003, 197081001, 197093005, 197116004, 155781003, 197082008, 155780002, 271365001, 31113003, 397881000, 63532004
English Diverticula of intestine NOS, Diverticula of the intestine NOS, Diverticular disease intestine, Diverticular disorder of intestine, Diverticulosis NOS, Diverticulosis unspecified, diverticula of intestine (diagnosis), diverticulosis (diagnosis), diverticulosis, diverticula of intestine, Diverticular disorders, Diverticulum intestinal, Diverticular disease of intestine, Diverticular disease of intestine NOS, intestinal diverticulum, Disease;diverticular;intestine, diverticulum intestinal, Diverticulosis NOS (disorder), Diverticular disease(& [of intestine]), Diverticulosis unspecified (disorder), Diverticular disorder of intestine (disorder), Diverticular disease(& [of intestine]) (disorder), Diverticula of the intestine NOS (disorder), Diverticula of intestine, Diverticular disease, DD - Diverticular disease, Diverticula of intestine (disorder), Diverticular disease (disorder), Diverticulum of intestine, Diverticula of intestine, NOS, Diverticular Disorder, Diverticulosis, diverticular disease
Italian Disturbi diverticolari, Diverticolo dell'intestino, Malattia diverticolare, Diverticoli dell'intestino, Diverticolosi
Dutch diverticulose, divertikelziekte, darmdivertikels, Diverticulose/diverticulitis, darmdivertikel, divertikelaandoeningen, Divertikelziekte, Diverticulosis
French Diverticulite de l'intestin, Maladie diverticulaire, Diverticulose, Affections diverticulaires, Diverticule intestinal
German Divertikelerkrankung, Divertikel des Darms, Divertikulose, Divertikulose des Darmes, Darmdivertikel, Divertikelerkrankungen
Portuguese Divertículos do intestino, Doença diverticular, Diverticulose, Afecções diverticulares, Divertículo intestinal
Spanish Enfermedad diverticular, Divertículos de intestino, Diverticulosis, trastorno diverticular de intestino (trastorno), Diverticulosis NOS, trastorno diverticular de intestino, diverticulosis no especificada, diverticulosis, SAI (trastorno), divertículos intestinales, SAI (trastorno), diverticulosis, SAI, divertículos intestinales, SAI, diverticulosis no especificada (trastorno), diverticulosis, divertículo del intestino (trastorno), divertículo del intestino, divertículo intestinal, enfermedad diverticular (trastorno), enfermedad diverticular, Trastornos diverticulares, Divertículo intestinal
Japanese 憩室疾患, 腸憩室, 憩室症, 憩室性疾患, チョウケイシツ, ケイシツセイシッカン, ケイシツショウ, ケイシツシッカン
Czech Divertikulóza, Divertikl střeva, Divertikly střeva, Divertikulární poruchy, Divertikulární nemoc, divertikulóza
Korean 창자의 곁주머니(게실)병
Hungarian Diverticulosis, Intestinalis diverticulum, Bél diverticulumai, Diverticulum betegségek, Diverticulosisos betegség
Norwegian Divertikulose