II. Definition

  1. Forward displacement of globe

III. Causes: Duration

  1. Acute Onset
    1. Orbital disease
    2. Cavernous Sinus Disease
  2. Chronic Onset
    1. Graves Disease (autoimmune Thyroiditis)
    2. Orbital Mass lesion!

IV. Causes: Symmetry

  1. Bilateral Proptosis
    1. Graves Disease (autoimmune Thyroiditis)
  2. Unilateral Proptosis
    1. Orbital Tumor or Neoplasm
    2. Orbital pseudotumor (autoimmune eye inflammation)
      1. Presents with lid inflammation, Eye Pain and ophthlmoplegia (eye muscle paralysis)
    3. Cavernous Sinus Thrombosis
      1. Present with ill appearance with Headache, Vomiting, vision change and Altered Level of Consciousness
    4. Endophthalmitis

V. Signs

  1. Stand behind seated patient and look down
    1. Compare positions of both Corneas
  2. Viewing from front
    1. Ring of white Sclera seen between iris and lids

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Ontology: Exophthalmos (C0015300)

Definition (MSHCZE) Vystoupení (vysunutí) oka z očnice. E. může být jedno- nebo oboustranný. Příč.: záněty a nádory v očnici, trombóza nitrolebečních splavů, nemoci štítné žlázy (hypertyreóza). Je-li nadměrný, vede k lagoftalmu a ohrožení zraku. Opak enoftalmus. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
Definition (NCI) A protrusion of the eyeball from the socket.
Definition (NCI) Abnormal protrusion of one or both eyes from the socket; causes include hyperthyroidism (particularly Graves disease); bleeding behind the eye; infection, inflammation, or tumors of the orbit; and vascular disorders.
Definition (MSH) Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye.
Definition (CSP) protrusion of one or both eyeballs; can be congenital and familial, or due to pathology, such as a retroorbital tumor (usually unilateral) or thyroid disease (usually bilateral).
Concepts Disease or Syndrome (T047)
MSH D005094
ICD9 376.30
ICD10 H05.20
SnomedCT 155200004, 267746003, 18265008
English Exophthalmos, Proptoses, Proptosis, EXOPHTHALMOS, Exophthalmos NOS, Exophthalmos, unspecified, Exophthalmus, Ocular proptosis, proptosis, exophthalmos (diagnosis), eyes bulging out as symptom, proptosis (physical finding), eyes bulging out, exophthalmos, eyes bulging out (symptom), Bulging eyes, Unspecified exophthalmos, Exophthalmos [Disease/Finding], bulging eye, bulging eyes, exophthalmia, Eye bulging, Prolapsed globe, Eye displaced forwards, Exophthalmia, Exophthalmos (disorder), Exophthalmos, NOS, Proptosis, NOS
French EXOPHTALMIE, Exophtalmie SAI, Exophtalmie, non précisée, Yeux protubérants, Exophtalmie, Proptose
German EXOPHTHALMUS, Exophthalmus, unspezifisch, hervortretende Augen, Exophthalmus NNB, Proptosis, Exophthalmus, Protrusio bulbi
Dutch exoftalmie, niet-gespecificeerd, uitpuilende ogen, proptosis, exoftalmie NAO, exoftalmie, Exophtalmus, Proptosis
Italian Esoftalmo NAS, Esoftalmo, non specificato, Gonfiore agli occhi, Proptosi, Esoftalmo
Portuguese Exoftalmo NE, Exoftalmos NE, Olhos salientes, EXOFTALMOS, Exoftalmia, Proptose
Spanish Ojos saltones, Exoftalmos no especificado, Exoftalmos NEOM, EXOFTALMOS, exoftalmia, exoftalmos (trastorno), exoftalmía, exoftalmía (trastorno), exoftalmos, Exoftalmos, proptosis, Proptosis, Exoftalmia
Japanese 眼球突出症、詳細不明, 眼球突出症NOS, ガンキュウトッシュツショウ, ガンキュウトッシュツショウNOS, ガンキュウトッシュツ, ガンキュウトッシュツショウショウサイフメイ, 眼球突出, 眼球突出症
Swedish Glosögdhet
Czech exoftalmus, Blíže neurčený exoftalmus, Proptóza, Exoftalmus, Exoftalmus NOS
Finnish Eksoftalmus
Russian EKZOFTAL'M, PROPTOZ GLAZNOGO IABLOKA, ПРОПТОЗ ГЛАЗНОГО ЯБЛОКА, ЭКЗОФТАЛЬМ
Croatian Not Translated[Exophthalmos]
Polish Wytrzeszcz
Hungarian Proptosis, Kidülledő szemek, Exophthalmus, nem meghatározott, Exophthalmus, Exophthalmus k.m.n.
Norwegian Proptose, Utstående øyne, Eksoftalmus