II. Epidemiology

  1. Occurs in all ages

III. Pathophysiology

  1. Meibomian Gland affected
    1. Sebaceous Gland in lid tarsal plate
  2. Chronic granulomatous inflammation

IV. Symptoms

  1. Gradually developing, painless Eyelid Swelling for >2 weeks
    1. Contrast with shorter durations for Hordeolum development

V. Signs

  1. Small non-tender Nodule ("English pea")
  2. Deep cyst inside lid (not on margin)
  3. Adjacent to palpebral Conjunctiva
    1. Conjunctiva is red and elevated in affected area

VI. Differential Diagnosis

  1. Internal Hordeolum (stye)
    1. Painful, inflamed, infected lid margin as contrasted with the painless, non-inflamed, sterile Chalazion
  2. Lid malignancy
    1. Biopsy needed if Chalazia recur in same area

VII. Management

  1. Small chronic Chalazia need no treatment
  2. Larger chronic Chalazia
    1. Indications for treatment
      1. Cosmetic swelling
      2. Secondary Astigmatism from pressure on globe
    2. Refer to Ophthalmology for treatment
      1. Surgical Excision (preferred for larger lesions)
      2. Local Corticosteroid Injection
  3. Infected Chalazia
    1. Same management as for Hordeolum

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Ontology: Meibomian Cyst (C0007933)

Definition (MSHCZE) Lat. vlčí zrno; obv. chronický granulomatózní zánět žlázky očního víčka (tzv. meibomské žlázky), jemuž předcházel akutní zánět. Projeví se bolestí a zarudnutím víčka, na jehož spodní (spojivkové) straně prosvítá zhnisaná žlázka. Odstraňuje se drobným chirurgickým zákrokem. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
Definition (MSH) A non-neoplastic cyst of the MEIBOMIAN GLANDS of the eyelid.
Concepts Disease or Syndrome (T047)
MSH D017043
ICD9 373.2
ICD10 H00.1
SnomedCT 155172004, 155173009, 397514009, 267736000, 1482004
English Chalazion, Meibomian Cyst, Cyst, Meibomian, chalazion (diagnosis), chalazion, chalazion (physical finding), Meibomian (gland) cyst, Chalazion [Disease/Finding], Chalazia, meibomian cyst, cysts meibomian, Cyst;meibomian, chalazions, tarsal cyst, Meibomian gland cyst, Tarsal cyst, Meibomian cyst, Chalazion (disorder), cyst; meibomian, meibomian; cyst, meibomians cyst
Dutch cyste van Meibom, Meibom; cyste, cyste; Meibom, chalazion, Chalazion, Meibom-cyste
French Kyste des glandes de Meibomius, Chalazion, Kyste de la glande de Meibomius, Kyste meibomien
Italian Cisti di Meibomio, Cisti meibomiana, Calazio
Portuguese Quisto das glândulas de Meibomius, Cisto das Glândulas de Meibômio, Calazião, Chalázio, Calázio, Cisto Meibomiano
Spanish Quiste de glándula de Meibomio, Chalazión, Quiste de las Glándulas de Meibomio, Calacio, Chalacion, calacio, chalazión (trastorno), chalazión, quiste de Meibomio, quiste de la glándula de Meibomio, quiste tarsiano, Quiste Meibomiano
Swedish Kronisk vagel
Japanese サンリュウシュ, マイボームセンノウホウ, さん粒腫, Meibom腺嚢胞, Meibom嚢胞, 霰粒腫, マイボーム腺嚢胞
Czech chalazion, meibomská cysta, Meibomská cysta, Chalazion, zánět Meibomovy žlázy, vlčí zrno
Finnish Luomirakkula
Russian KHALAZION, MEIBOMIEVOI ZHELEZY KISTA, МЕЙБОМИЕВОЙ ЖЕЛЕЗЫ КИСТА, ХАЛАЗИОН
Korean 콩다래끼
Polish Gradówka, Chalazion, Torbiel gruczołu Meiboma
Hungarian Chalazion, Meibom cysta
Norwegian Chalazion, Haglkorn, Meiboms cyste
German Chalazion, Hagelkorn, Meibom-Zyste