II. Causes

  1. Bacteria
    1. Pseudomonas (esp. Soft Contact Lenses worn overnight)
  2. Fungus

III. Symptoms

IV. Signs

  1. Infiltrate (White Spot) on Cornea
    1. Seen without Fluorescein
  2. Overlying Corneal Epithelial Disruption
  3. Iritis
  4. Hypopyon

V. Labs

  1. Culture discharge

VI. Management

  1. Urgent Ophthalmology referral
  2. Topical Antibiotics - broad spectrum around the clock
    1. Tobramycin
    2. Gentamicin
    3. Norfloxacin
    4. Ciprofloxacin
  3. Cycloplegic
    1. Homatropine 5% tid
    2. Atropine 1% bid

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Ontology: Corneal Ulcer (C0010043)

Definition (NCI_FDA) Area of epithelial tissue loss from corneal surface; associated with inflammatory cells in the cornea and anterior chamber.
Definition (NCI) Area of epithelial tissue loss from corneal surface; associated with inflammatory cells in the cornea and anterior chamber.
Definition (NCI_CTCAE) A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber.
Definition (MSH) Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
Definition (CSP) loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
Concepts Disease or Syndrome (T047) , Acquired Abnormality (T020)
MSH D003320
ICD9 370.00, 370.0
ICD10 H16.0 , H16.00
SnomedCT 193759000, 193763007, 193758008, 155152009, 275501000009101, 91514001
English Corneal Ulcer, Keratitides, Ulcerative, Keratitis, Ulcerative, Ulcer, Corneal, Ulcerative Keratitides, Ulcerative Keratitis, cornea ulcer, CORNEAL ULCERATION, corneal ulcer (diagnosis), corneal ulceration (physical finding), corneal ulcer, corneal ulceration, Corneal ulcer NOS, Unspecified corneal ulcer, Corneal Ulcer [Disease/Finding], Ulcer;corneal, corneal ulcers, ulcer cornea, cornea ulcers, Corneal ulcerations, Corneal ulcer NOS (disorder), Unspecified corneal ulcer (disorder), Ulcerative keratitis (disorder), Ulcerative keratitis, Cornea--Ulcers, ULCER, CORNEAL, CORNEAL ULCER, Corneal ulcer, Corneal ulcer (disorder), cornea; erosion, cornea; ulcer, erosion; cornea, ulcer; cornea, ulcerative; keratitis, Corneal ulcer, NOS, ulcerative keratitis, Corneal ulcer, unspecified, Ulcer corneal, Corneal ulceration
Dutch ulceratieve keratitis, cornea ulcus, niet-gespecificeerd, cornea ulcus, cornea ulceratie, ulcus corneae, cornea; erosie, cornea; ulcus, erosie; cornea, ulceratief; keratitis, ulcus; cornea, Cornea-ulcus, Hoornvliesulcus, Keratitis, ulceratieve, Ulcus corneae
German Ulzerative Keratitis, Ulkus der Hornhaut, Hornhautulzeration, Hornhautulkus, unspezifisch, HORNHAUTULZERATION, Ulcus corneae, Keratitis, ulzerative, Hornhautulkus, Kornea-Ulkus, Hornhautgeschwür, Korneageschwür
Portuguese Queratite ulcerosa, Úlcera da córnea, Úlcera da córnea NE, Ulceração da córnea, ULCERACAO DA CORNEA, Ceratite Ulcerativa, Úlcera da Córnea
Spanish Queratitis ulcerosa, Úlcera de córnea, Úlcera corneal no especificada, Úlcera corneal, Ulceración corneal, CORNEA, ULCERACION, úlcera de córnea no especificada, úlcera de córnea no especificada (trastorno), úlcera de córnea, SAI (trastorno), úlcera de córnea, SAI, úlcera corneal (trastorno), úlcera corneal, Queratitis Ulcerativa, Úlcera de la Córnea
French Ulcération de la cornée, Ulcère cornéen non précisé, ULCERATION CORNEENNE, Kératite ulcérative, Ulcère de la cornée, Ulcère cornéen, Kératite ulcéreuse
Italian Ulcera dela cornea, Ulcerazione corneale, Ulcera corneale, non specificata, Cheratite ulcerativa, Ulcera corneale
Japanese 角膜潰瘍形成, 角膜潰瘍、詳細不明, カクマクカイヨウ, カイヨウセイカクマクエン, カクマクカイヨウケイセイ, カクマクカイヨウショウサイフメイ, 潰瘍-角膜, 角膜潰瘍, 潰瘍性角膜炎, 角膜炎-潰瘍性
Swedish Hornhinnesår
Czech rohovka - vřed, Ulcerace rohovky, Nespecifikovaný vřed na rohovce, Rohovkový vřed, Vřed rohovky, Vředovitá keratitida
Finnish Sarveiskalvon haavauma
Russian KERATIT IAZVENNYI, ROGOVITSY IAZVA, КЕРАТИТ ЯЗВЕННЫЙ, РОГОВИЦЫ ЯЗВА
Korean 각막 궤양
Polish Wrzód rogówki
Hungarian Cornea fekély, Ulcerativ keratitis, Cornealis fekély, nem meghatározott, Cornealis fekély, Cornealis ulceratio
Norwegian Hornhinnesår, Ulcerøs keratitt, Keratitt, ulcerøs, Corneaulcus, Corneasår, Ulcus corneae, Kornealsår