II. Pathophysiology

  1. Infection by Fusobacterium necrophorium
    1. Responsible for 10% of acute Pharyngitis cases in young adults and adolescents
  2. Occurs with contiguous infection from Pharyngitis (typically) or Dental Infection to lateral pharyngeal space
  3. Results in septic Thrombophlebitis of internal Jugular Vein

III. Epidemiology

  1. Adolescents and young adults make up majority of cases

IV. Signs

  1. Fever
  2. Tonsillar exudates
  3. Anterior Cervical Lymphadenopathy
  4. Cough absent

V. Complications

  1. High morbidity and mortality
  2. Metastatic infection
  3. Septic pulmonary emboli

VI. Management: Consider empiric treatment

VII. References

  1. Edson (2011) Internal Medicine, Mayo Conference, Kauai

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