II. Epidemiology

  1. Incidence highest over 60 years old
  2. Men more commonly affected

III. Pathophysiology

  1. Squamous Cell Carcinoma (90% of malignant Larynx)

IV. Risk Factors

  1. Tobacco abuse
  2. Alcohol Abuse
  3. Elderly

V. Symptoms

  1. Chronic Hoarseness (longer than 2 weeks)
  2. Pharyngitis
  3. Otalgia
  4. Dysphagia
  5. Dyspnea

VI. Signs: Laryngeal Exam

  1. Early Findings
    1. Small, white Plaques or erythematous Nodule
    2. Findings may be subtle
  2. Advanced findings
    1. Exophytic mass lesion or ulceration on Vocal Cords
    2. Immobility of the vocal cord may suggest invasion

VII. Management

  1. Surgical excision with or without radiation

VIII. Prognosis:

  1. Five year survival if lesion on true cords: >80%
  2. Five year survival if lesion above true cords: >50%

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Ontology: Laryngeal neoplasm (C0023055)

Definition (MSHCZE) Karcinom nebo nádory hrtanu (LARYNX), či jakékoli jeho části: GLOTTIS, EPIGLOTIS, LARYNGÁLNÍ CHRUPAVKA, LARYNGÁLNÍ SVALY a HLASIVKY.
Definition (NCI) A benign or malignant neoplasm involving the larynx.
Definition (CSP) new abnormal laryngeal tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease; includes cancers or tumors of the larynx or any of its parts, the glottis, epiglottis, laryngeal cartilages, laryngeal muscles, and vocal cords.
Definition (MSH) Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.
Concepts Neoplastic Process (T191)
MSH D007822
SnomedCT 126692004
English Laryngeal Neoplasms, Neoplasm, Laryngeal, Neoplasms, Laryngeal, larynx neoplasm, LARYNGEAL NEOPL, NEOPL LARYNGEAL, LARYNX NEOPL, neoplasm of larynx, neoplasm of larynx (diagnosis), Laryngeal neoplasia, Laryngeal neoplasm NOS, Neoplasm larynx, Larynx Neoplasms, Neoplasm, Larynx, Neoplasms, Larynx, Laryngeal Neoplasms [Disease/Finding], laryngeal neoplasia, larynx tumor, laryngeal neoplasms, neoplasms larynx, larynx tumors, neoplasm larynx, tumor larynx, tumor of larynx, laryngeal neoplasm, Larynx--Tumors, Tumor of larynx, Tumour of larynx, Neoplasm of larynx (disorder), Neoplasm of larynx, Laryngeal Neoplasm, Larynx Neoplasm, Laryngeal Tumor, Larynx Tumor, Neoplasm of Larynx, Neoplasm of the Larynx, Tumor of Larynx, Tumor of the Larynx, Laryngeal neoplasm
Italian Tumore della laringe, Tumore della laringe NAS, Neoplasia della laringe, Neoplasie laringee, Neoplasie della laringe
Dutch neoplasma larynx, larynxneoplasie, larynxneoplasma NAO, larynxneoplasma, Gezwel, larynx-, Gezwellen, larynx-, Larynxgezwel, Larynxgezwellen, Larynxtumor
French Tumeur du larynx SAI, Néoplasie laryngée, Tumeur laryngée, Tumeurs du larynx, Tumeurs laryngées
German laryngeale Neoplasie, Neubildung des Kehlkopfs NNB, Neubildung der Larynx, Neubildung des Kehlkopfes, Kehlkopftumoren, Larynxtumoren
Portuguese Neoplasia da laringe, Neoplasia da laringe NE, Tumor laríngeo, Neoplasias da Laringe, Neoplasias Laríngeas
Spanish Neoplasia laríngea NEOM, Neoplasia de laringe, neoplasia de la laringe (trastorno), neoplasia de la laringe, Neoplasia laríngea, Neoplasias Laríngeas, Neoplasias de la Laringe
Japanese 喉頭新生物, 喉頭新生物NOS, コウトウシンセイブツ, コウトウシンセイブツNOS, 喉頭腫瘍
Swedish Struphuvudtumörer
Finnish Kurkunpään kasvaimet
Czech Novotvar hrtanu, Novotvar laryngu, Novotvar laryngu NOS, Neoplazie hrtanu, nádory hrtanu, nádory laryngu, laryngeální nádory, larynx - nádory
Polish Nowotwory krtani
Hungarian Gége daganata, Gége neoplasia, Gégedaganat, Gége neoplasia k.m.n.
Norwegian Strupeneoplasmer, Larynxsvulster, Strupetumorer, Strupesvulster, Larynxneoplasmer, Larynxtumorer