II. Indication: Gestational DiabetesScreening Test

  1. All pregnant patients at 24-28 weeks gestation
  2. Test with initial Prenatal Labs if indicated
    1. Overweight patient
    2. Family History of Diabetes Mellitus
    3. Age over 30 years
    4. Prior history of Glucose Intolerance
    5. Prior pregnancy complication
      1. Fetal Macrosomia
      2. Intrauterine Fetal Demise (Stillborn)
      3. Pregnancy Induced Hypertension (PIH)
      4. Polyhydramnios
      5. Congenital defect

III. Protocol

  1. Patient ingests 50 gram oral Glucose (e.g. Glucola Drink)
  2. Serum Glucose measured after 1 hour

IV. Interpretation

  1. Serum Glucose >130 mg/dl (7.2 mmol/L) suggests gestation diabetes
  2. Obtain Glucose Tolerance Test 3 hour if positive
    1. Empiric Gestational Diabetes Management for GCT >200 mg/dl (without a 3 hour GTT)

V. Efficacy: Using cut-off of 130 mg/dl

  1. Test Sensitivity: 99% (85% if 140 mg/dl cut-off used)
  2. Test Specificity: 77% (86% if 140 mg/dl cut-off used)

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Ontology: Glucose^1H post 50 g glucose PO:MCnc:Pt:Ser/Plas:Qn (C0363638)

Concepts Clinical Attribute (T201)
LNC 1504-0
English Glucose [Mass/volume] in Serum or Plasma --1 hour post 50 g glucose PO, Glucose^1H post 50 g glucose PO:MCnc:Pt:Ser/Plas:Qn, Glucose^1 hour post 50 g glucose Oral:Mass Concentration:Point in time:Serum/Plasma:Quantitative, Glucose 1h p 50 g Glc PO SerPl-mCnc