II. Causes: Dermatologic Conditions

III. Causes: Systemic

  1. Iron Deficiency Anemia
  2. Severe Chronic Renal Failure (Uremic Pruritus)
  3. Neurodermatitis or Delusions of Parasitosis
  4. Polycythemia Rubra Vera (30-50%)
    1. Provoked by hot shower or bath
    2. Pricking type itch may persist for hours
  5. Hodgkin's Lymphoma
  6. Malignant Carcinoid
  7. Multiple Myeloma
  8. Scleroderma
  9. Malignant Carcinoid
  10. Rapid weight loss (e.g. Anorexia Nervosa)
  11. Hyperthyroidism (4-11% long-standing Grave's Disease)
  12. Urticaria
  13. Cholestasis (bile salt protease release in skin)
    1. See Cholestasis associated Pruritus
  14. Systemic infection
    1. HIV Infection (see Pruritus in HIV)
    2. Filariasis
    3. Schistosomiasis
    4. Onchocerciasis (river blindness)
    5. Ascariasis
    6. Hookworm
    7. Trichinosis
    8. Parvovirus B19

V. Causes: Exposure related Pruritus

  1. Water
    1. Aquagenic Pruritus
      1. Intense distressing itch after water contact
    2. CholinergicUrticaria
    3. Polycythemia Vera (follows warm bath)
    4. Swimmer's Itch
  2. Pregnancy (See Pruritus in Pregnancy)
    1. Pruritic Urticarial Papules and Plaques of Pregnancy
    2. Prurigo of Pregnancy
    3. Herpes Gestationis or Pemphigoid Gestationis
    4. Cholestasis associated Pruritus (Prurigo gravidarum)
    5. Pruritic Folliculitis of Pregnancy
    6. Atopic Dermatitis
    7. Contact Dermatitis
  3. Medications
    1. Itraconazole, Fluconazole, Ketoconazole
    2. Niacinamide
    3. B Vitamins
    4. Aspirin
    5. Quinidine
    6. Ointments with high concentrations of inert oil
    7. Narcotics (especially via spinal administration)
    8. Hypersensitivity Reaction
      1. Rifampin
      2. Vancomycin
  4. Allergen or irritant exposure (e.g. Contact Dermatitis)
    1. Heat exposure: Miliaria rubra (Prickly heat)
    2. Cat exposure
    3. Fiberglass exposure (Fiberglass Dermatitis)

VII. References

  1. See Pruritus

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