II. Pathophysiology

  1. Skin Reaction to Cold, damp conditions

III. Symptoms

  1. Onset
    1. Lesions following cold exposure
  2. Location:
    1. Inflammatory lesions of hands and feet
  3. Associated symptoms
    1. Lesions itch, burn or are painful
  4. Course
    1. Develops over hours or days and slowly subsides

IV. Signs

  1. Rash on hands and feet
    1. Multiple erythematous, purplish Papules or Nodules

V. Lab: Skin biopsy

  1. Blood vessel wall thickening
  2. Perivascular lymphocytic infiltrates
  3. Edema of papillary Dermis

VI. Management

  1. Rest
  2. Warmth
  3. Antipruritics
  4. Analgesics
  5. Nifedipine 20 mg PO tid

VII. Prevention

  1. Adequate clothing and home heating
  2. Short course of UV light at the beginning of winter

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Ontology: Chilblains (C0008058)

Definition (NCI) A rare condition characterized by skin inflammation, blister formation, swelling and ulcerations in the extremities. It occurs in persons exposed to cold temperatures.
Definition (MSH) Recurrent localized itching, swelling and painful erythema on the fingers, toes or ears, produced by exposure to cold.
Concepts Disease or Syndrome (T047)
MSH D002647
ICD9 991.5
ICD10 T69.1
SnomedCT 157719006, 269421007, 37869000
English Effects of chilblains, chilblains (diagnosis), chilblains, erythema pernio, Chillblains, Chilblains [Disease/Finding], chillblains, chilblained, chilblain, chilblain disorder, perniosis, Perniosis, Idiopathic, Perniosis, Idiopathic Perniosis, Idiopathic Pernioses, Pernioses, Idiopathic, Pernioses, Pernio, Pernios, Erythema pernio, Chilblain, Chilblains (disorder), cold; adverse effect, chilblains, erythema; pernio, adverse effect; cold, chilblains, pernio; erythema, pernio, Chilblains
Dutch pernio, winterhanden, erytheem; pernio, koude; ongewenst gevolg, winterhanden en -voeten, ongewenst gevolg; koude, winterhanden en -voeten, pernio; erytheem, koubulten, Hand en -voet, winter-, Handen en -voeten, winter-, Winterhand en -voet, Winterhanden en -voeten
French Engelure, Engelures
German Frostbeule, Frostbeulen, Pernio
Portuguese Frieiras, Congelamento (chilblains), Eritema Pérnio, Perniose, Geladura, Psicose infantil, Pérnio
Spanish Sabañón, Sabañones, Sabanones, eritema pernio, perniosis, sabañones (trastorno), sabañones, Perniosis, Eritema Pernio
Japanese 凍瘡, トウソウ
Swedish Köldknölar
Czech oznobenina, Omrzliny, Omrznutí
Finnish Kylmänkyhmyt
Russian OZNOBLENIE, OBMOROZHENIE, OTMOROZHENIE I-OI STEPENI, ОБМОРОЖЕНИЕ, ОЗНОБЛЕНИЕ, ОТМОРОЖЕНИЕ I-ОЙ СТЕПЕНИ
Korean 동창
Polish Odmroziny
Hungarian Fagyási sérülés, Pernio
Norwegian Frostknuter, Pernio, Perniose, Idiopatisk perniose
Italian Geloni